HitPredict

Interactor 1: BRE1A (Q5DTM8)
E3 ubiquitin-protein ligase BRE1A (BRE1-A) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A)
Gene: Rnf20

Interactor 2: H2B1B (Q64475)
Histone H2B type 1-B (H2B-clustered histone 3) (h2B-143)
Gene: H2bc3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35074526
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 973 Mm			1 126
+	Hs
		1087184 BRE1A_HUMAN (1-973): 2.37e-75: 269: 97.64		H2B2E_HUMAN (1-126): 2.28e-54: 168: 96.03
+	Hs
		707654 BRE1A_HUMAN (1-973): 2.37e-75: 269: 97.64		H2B1B_HUMAN (1-126): 4.91e-54: 167: 97.62
+	Hs
		256269 BRE1B_HUMAN (18-972): 1.34e-63: 235: 56.05		H2B2E_HUMAN (1-126): 2.28e-54: 168: 96.03
+	Hs
		256219 BRE1B_HUMAN (18-972): 1.34e-63: 235: 56.05		H2B1B_HUMAN (1-126): 4.91e-54: 167: 97.62
+	Sc
		356028 BRE1_YEAST (503-972): 5.14e-66: 237: 18.89		H2B2_YEAST (3-125): 4.19e-41: 134: 71.55
+	Sc
		355667 BRE1_YEAST (503-972): 5.14e-66: 237: 18.89		H2B1_YEAST (3-125): 1.43e-35: 120: 71.55
+	Hs
		241465 MYH11_HUMAN (1-760): 4.98e-34: 144: 12.81		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03
+	Hs
		728463 MYH11_HUMAN (1-760): 4.98e-34: 144: 12.81		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		725214 MYH10_HUMAN (302-939): 1.95e-30: 132: 9.40		H2B1H_HUMAN (1-126): 2.16e-54: 168: 96.03
+	Hs
		241464 MYH10_HUMAN (302-939): 1.95e-30: 132: 9.40		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03
+	Hs
		725133 MYH10_HUMAN (302-939): 1.95e-30: 132: 9.40		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		725122 MYH10_HUMAN (302-939): 1.95e-30: 132: 9.40		H2B1D_HUMAN (1-126): 1.09e-53: 166: 96.83
+	Hs
		725231 MYH10_HUMAN (302-939): 1.95e-30: 132: 9.40		H2B1L_HUMAN (1-126): 9.05e-53: 163: 96.83
+	Hs
		724951 MYH9_HUMAN (306-937): 1.76e-28: 126: 11.29		H2B1H_HUMAN (1-126): 2.16e-54: 168: 96.03
+	Hs
		241463 MYH9_HUMAN (306-937): 1.76e-28: 126: 11.29		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03
+	Hs
		724751 MYH9_HUMAN (306-937): 1.76e-28: 126: 11.29		H2B1C_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		724734 MYH9_HUMAN (306-937): 1.76e-28: 126: 11.29		H2B1D_HUMAN (1-126): 1.09e-53: 166: 96.83
+	Hs
		1274476 MYH2_HUMAN (437-954): 1.25e-21: 104: 11.75		H2B1H_HUMAN (1-126): 2.16e-54: 168: 96.03
+	Hs
		621614 LAMA2_HUMAN (460-913): 7.9e-14: 78.3: 14.26		H2B1H_HUMAN (1-126): 2.16e-54: 168: 96.03
+	Hs
		148194 CTRO_HUMAN (240-915): 1.47e-13: 77.6: 16.64		H2B1K_HUMAN (1-126): 4.91e-54: 167: 96.03