HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: YTHD1 (Q9BYJ9)
YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1)
Gene: YTHDF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	29395067, 34133714
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2229 Hs			1 559
+	Hs
		1127740 PRC2B_HUMAN (1-2229): 0: 619: 100.00		YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72
+	Hs
		1127634 PRC2B_HUMAN (1-2229): 0: 619: 100.00		YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91
+	Hs
		1317062 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		YTHD1_HUMAN (1-559): 2.02e-141: 422: 100.00
+	Hs
		1377926 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72
+	Hs
		1192419 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91
+	Hs
		1301022 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72
+	Hs
		821029 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		YTHD1_HUMAN (1-559): 2.02e-141: 422: 100.00
+	Hs
		821100 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72
+	Hs
		820960 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91
+	Hs
		1300943 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		YTDC2_HUMAN (226-535): 2.61e-51: 192: 23.18
+	Dm
		113976 M9PB30_DROME (1183-1955): 1.05e-13: 79.8: 9.22		M9PB30_DROME (54-344): 7.98e-11: 67.6: 14.53
+	Mm
		1351630 PCLO_MOUSE (15-1858): 1.65e-14: 82.4: 8.18		PCLO_MOUSE (139-370): 1.14e-09: 63.8: 14.52
+	Hs
		1300971 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		CHD7_HUMAN (14-322): 4.11e-10: 65: 14.24
+	Hs
		867119 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		SC24C_HUMAN (10-290): 4.07e-10: 65: 12.37