Interactor 1: WDR43 (Q15061)
WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)
Gene: WDR43

Interactor 2: UTP4 (Q969X6)
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component)
Gene: UTP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 28514442, 34079125, 33961781, 35271311, 22916032, 24219289, unassigned3799
Identification Methods affinity chromatography technology, proximity labelling technology, tandem affinity purification, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001650 - fibrillar center
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 677
Hs

1 686
+ Sc
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025