HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26638075, 26496610, 34079125
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 669
+	Hs
		230542 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		LZTS3_HUMAN (1-669): 7.26e-32: 133: 31.62
+	Hs
		1113836 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1012560 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88
+	Hs
		1146002 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44
+	Hs
		1137872 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68
+	Hs
		725179 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		1051301 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		1068548 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		1113789 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		148466 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		725097 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		528432 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94
+	Hs
		528435 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Hs
		502901 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93
+	Hs
		148461 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		725095 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		528356 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH6_HUMAN (140-554): 2.32e-09: 63.1: 9.14