HitPredict

Interactor 1: GCK1 (H2L099)
Germinal center kinase 1 (EC 2.7.11.1)
Gene: gck-1

Interactor 2: 2AAA (Q09543)
Probable serine/threonine-protein phosphatase PP2A regulatory subunit (Protein phosphatase PP2A regulatory subunit A)
Gene: paa-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28285997
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Ce			1 590
+	Hs
		138809 STK25_HUMAN (26-389): 1.3e-149: 441: 64.32		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		692001 MARK3_HUMAN (11-645): 1.1e-140: 429: 18.81		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		138810 STK25_HUMAN (26-389): 1.3e-149: 441: 64.32		2AAB_HUMAN (11-590): 1.79e-151: 450: 62.24
+	Hs
		718029 STK26_HUMAN (29-350): 2.5e-139: 414: 66.56		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		717875 MARK2_HUMAN (7-634): 7.22e-134: 413: 17.27		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		717801 KCC2G_HUMAN (29-557): 1.4e-134: 407: 14.63		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		717940 MARK4_HUMAN (2-637): 9.84e-131: 404: 19.29		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		717693 AKT1_HUMAN (2-355): 4.86e-134: 403: 21.21		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		718186 STK26_HUMAN (29-350): 2.5e-139: 414: 66.56		2AAB_HUMAN (11-590): 1.79e-151: 450: 62.24
+	Hs
		718076 STK24_HUMAN (27-399): 3.38e-127: 384: 60.00		2AAA_HUMAN (1-590): 4.08e-159: 469: 62.20
+	Hs
		718206 STK24_HUMAN (27-399): 3.38e-127: 384: 60.00		2AAB_HUMAN (11-590): 1.79e-151: 450: 62.24
+	Dm
		782729 AKT1_DROME (1-347): 1.23e-127: 391: 24.51		2AAA_DROME (1-580): 1.72e-142: 427: 57.76
+	Dm
		782739 HIPPO_DROME (30-311): 8.23e-122: 378: 48.07		2AAA_DROME (1-580): 1.72e-142: 427: 57.76
+	At
		1182199 CIPKG_ARATH (20-366): 3.62e-130: 393: 24.65		2AAA_ARATH (89-589): 2.08e-50: 185: 18.45
+	At
		1182183 CIPKJ_ARATH (15-417): 2.86e-129: 391: 20.15		2AAA_ARATH (89-589): 2.08e-50: 185: 18.45
+	Hs
		164570 KCC2G_HUMAN (29-557): 1.4e-134: 407: 14.63		TNPO2_HUMAN (1-585): 1.41e-16: 85.6: 10.70
+	Hs
		164565 STK3_HUMAN (12-308): 3.91e-133: 401: 50.00		TNPO2_HUMAN (1-585): 1.41e-16: 85.6: 10.70
+	Hs
		164569 KCC2B_HUMAN (30-549): 7.26e-130: 399: 17.07		TNPO2_HUMAN (1-585): 1.41e-16: 85.6: 10.70
+	Hs
		605764 KAPCA_HUMAN (4-329): 8.63e-131: 390: 24.85		GCN1_HUMAN (18-527): 1.04e-16: 86.4: 13.61
+	Hs
		1096469 PAK1_HUMAN (3-303): 4.82e-125: 382: 43.05		GCN1_HUMAN (18-527): 1.04e-16: 86.4: 13.61