HitPredict

Interactor 1: PTN21 (Q16825)
Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1)
Gene: PTPN21

Interactor 2: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27880917, 27432908
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1174 Hs			1 1192
+	Hs
		1151996 PTN14_HUMAN (3-1174): 0: 819: 52.62		WWC2_HUMAN (1-1192): 0: 1073: 100.00
+	Hs
		1163737 PTN21_HUMAN (1-1174): 0: 903: 100.00		KIBRA_HUMAN (1-1192): 0: 925: 48.79
+	Hs
		1152014 PTN14_HUMAN (3-1174): 0: 819: 52.62		KIBRA_HUMAN (1-1192): 0: 925: 48.79
+	Hs
		320570 FARP2_HUMAN (16-539): 5.68e-131: 428: 21.17		KIBRA_HUMAN (1-1192): 0: 925: 48.79
+	Hs
		1311666 E41L3_HUMAN (15-899): 5.49e-128: 421: 17.33		KIBRA_HUMAN (1-1192): 0: 925: 48.79
+	Hs
		217475 E41L2_HUMAN (7-542): 1.68e-124: 409: 23.99		KIBRA_HUMAN (1-1192): 0: 925: 48.79
+	Hs
		538985 EPB41_HUMAN (2-590): 2.69e-116: 384: 21.14		KIBRA_HUMAN (1-1192): 0: 925: 48.79
+	Dm
		1464408 Q9V3V3_DROME (1-1174): 2.05e-150: 485: 22.70		KIBRA_DROME (8-1190): 0: 710: 29.60
+	Hs
		1163758 PTN21_HUMAN (1-1174): 0: 903: 100.00		WWP1_HUMAN (6-143): 3.65e-36: 150: 22.67
+	Hs
		1152039 PTN14_HUMAN (3-1174): 0: 819: 52.62		WWP1_HUMAN (6-143): 3.65e-36: 150: 22.67
+	Hs
		1152054 PTN14_HUMAN (3-1174): 0: 819: 52.62		WWOX_HUMAN (5-193): 8.82e-38: 149: 20.71
+	Hs
		1151991 PTN14_HUMAN (3-1174): 0: 819: 52.62		MAGI3_HUMAN (9-97): 1.56e-34: 146: 43.82
+	Hs
		1152030 PTN14_HUMAN (3-1174): 0: 819: 52.62		MAGI1_HUMAN (1-97): 8.81e-33: 140: 38.53
+	Hs
		132066 PTN14_HUMAN (3-1174): 0: 819: 52.62		WWP2_HUMAN (3-143): 7.2e-31: 133: 23.84
+	Hs
		1152041 PTN14_HUMAN (3-1174): 0: 819: 52.62		SAV1_HUMAN (4-88): 4.56e-27: 116: 38.82
+	Hs
		1331861 E41L5_HUMAN (18-493): 1.42e-136: 434: 22.73		SYT2_HUMAN (699-968): 6.94e-104: 336: 15.05
+	Dm
		1464417 Q9V3V3_DROME (1-1174): 2.05e-150: 485: 22.70		SUDX_DROME (3-143): 3.5e-31: 134: 23.23
+	Hs
		48804 E41L5_HUMAN (18-493): 1.42e-136: 434: 22.73		ESYT2_HUMAN (830-957): 2.95e-10: 66.9: 5.11
+	Hs
		1439015 E41L3_HUMAN (15-899): 5.49e-128: 421: 17.33		SMUF1_HUMAN (40-193): 2.99e-14: 79.6: 16.58
+	Hs
		48850 FARP1_HUMAN (5-537): 2.11e-124: 410: 20.59		ESYT2_HUMAN (830-957): 2.95e-10: 66.9: 5.11