Interactor 1: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Interactor 2: LST8 (Q9BVC4)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: MLST8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 28514442, 28489822, 22084251, 18030348, 31665642, 22307628, 24036451, 19299511, 35973513, 37120454, 17461779, 17565979, 18505677, 17599906, 18925875, 16919458, 21376236
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0007010 - cytoskeleton organization
GO:0030307 - positive regulation of cell growth
GO:0030838 - positive regulation of actin filament polymerization
GO:0031669 - cellular response to nutrient levels
and 6 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1708
Hs

1 326
+ Mm
+ Hs
+ Hs
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024