Protein: DUS5
Dual specificity protein phosphatase 5 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH3)

Gene: DUS5, DUSP5
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q16690

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001706 - endoderm formation
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703609

MK01
Mitogen-activated protein kinase 1

1

20

Small-scale

0.653

High

691759

MK03
Mitogen-activated protein kinase 3

1

20

Small-scale

0.647

High

274152

ANR17
Ankyrin repeat domain-containing protein 17

1

6

High-throughput

0.618

High

1161865

DUS5
Dual specificity protein phosphatase 5

1

15

High-throughput

0.618

High

1161870

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

6

High-throughput

0.618

High

334785

IPO7
Importin-7

2

3

High-throughput

0.584

High

982452

RS15
Small ribosomal subunit protein uS19

2

0

High-throughput

0.559

High

1055316

APLP2
Amyloid beta precursor like protein 2

1

5

High-throughput

0.536

High

1161878

LZTS2
Leucine zipper putative tumor suppressor 2

2

12

High-throughput

0.533

High

239069

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.513

High

391263

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

1161879

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

High-throughput

0.513

High

1161866

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

189175

IPO8
Importin-8

1

2

High-throughput

0.479

High

230032

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.479

High

320689

UBXN7
UBX domain-containing protein 7

1

1

High-throughput

0.479

High

475369

RS17
Small ribosomal subunit protein eS17

1

1

High-throughput

0.479

High

485645

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.479

High

911258

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.479

High

1061002

SRSF1
Serine/arginine-rich splicing factor 1

1

8

High-throughput

0.479

High

1099097

SRSF5
Serine/arginine-rich splicing factor 5

1

8

High-throughput

0.479

High

1121031

BOP1
Ribosome biogenesis protein BOP1

1

1

High-throughput

0.479

High

1137052

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

4

High-throughput

0.479

High

1161868

FBX11
F-box only protein 11

1

3

High-throughput

0.479

High

1161871

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

2

High-throughput

0.479

High

1161873

NEDD1
Protein NEDD1

1

1

High-throughput

0.479

High

1161875

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

High-throughput

0.479

High

1161876

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

9

High-throughput

0.479

High

1161880

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.479

High

1161881

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1161884

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.479

High

160093

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

0

High-throughput

0.458

High

220694

DENR
Density-regulated protein

1

0

High-throughput

0.458

High

799907

COIL
Coilin

1

0

High-throughput

0.458

High

859302

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

926182

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.458

High

985475

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

1161867

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.458

High

1161877

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.458

High

1161882

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.458

High

1161883

DCA16
DDB1- and CUL4-associated factor 16

1

0

High-throughput

0.458

High

1161885

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.458

High

248212

NDK8
Putative nucleoside diphosphate kinase

1

6

High-throughput

0.445

High

229529

NRDC
Nardilysin

1

3

High-throughput

0.437

High

350661

DLGP3
Disks large-associated protein 3

1

1

High-throughput

0.437

High

1011621

RT35
Small ribosomal subunit protein mS35

1

2

High-throughput

0.437

High

1161874

AP3S1
AP-3 complex subunit sigma-1

1

7

High-throughput

0.437

High

125952

SMAP
Small acidic protein

1

0

High-throughput

0.249

Low

1161869

C2CD5
C2 domain-containing protein 5

1

0

High-throughput

0.249

Low

1161872

POPD1
Popeye domain-containing protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025