HitPredict

Interactor 1: K7EK07 (K7EK07)
Histone H3
Gene: H3-3B

Interactor 2: MSH6 (P52701)
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)
Gene: MSH6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Hs			1 1360
+	Hs
		913298 H31_HUMAN (1-132): 9.22e-58: 177: 96.21		MSH6_HUMAN (1-1360): 0: 1484: 100.00
+	Hs
		913300 H33_HUMAN (1-132): 3.67e-57: 175: 100.00		MSH6_HUMAN (1-1360): 0: 1484: 100.00
+	Hs
		883488 CENPA_HUMAN (9-132): 4.71e-44: 142: 50.38		MSH6_HUMAN (1-1360): 0: 1484: 100.00
+	Hs
		633309 H31_HUMAN (1-132): 9.22e-58: 177: 96.21		MSH3_HUMAN (173-1357): 0: 831: 22.16
+	Hs
		633310 H33_HUMAN (1-132): 3.67e-57: 175: 100.00		MSH3_HUMAN (173-1357): 0: 831: 22.16
+	Hs
		846585 H31_HUMAN (1-132): 9.22e-58: 177: 96.21		MSH2_HUMAN (393-1360): 0: 823: 21.88
+	Hs
		846587 H33_HUMAN (1-132): 3.67e-57: 175: 100.00		MSH2_HUMAN (393-1360): 0: 823: 21.88
+	Sc
		963693 H3_YEAST (1-132): 9.9e-52: 161: 90.91		MSH6_YEAST (115-1347): 0: 818: 28.54
+	Hs
		633300 CENPA_HUMAN (9-132): 4.71e-44: 142: 50.38		MSH3_HUMAN (173-1357): 0: 831: 22.16
+	Sc
		682932 H3_YEAST (1-132): 9.9e-52: 161: 90.91		MSH2_YEAST (408-1354): 0: 724: 20.96
+	Hs
		355489 H31_HUMAN (1-132): 9.22e-58: 177: 96.21		NSD2_HUMAN (4-411): 3.14e-80: 292: 17.44
+	Hs
		355497 H33_HUMAN (1-132): 3.67e-57: 175: 100.00		NSD2_HUMAN (4-411): 3.14e-80: 292: 17.44
+	Hs
		998773 H31_HUMAN (1-132): 9.22e-58: 177: 96.21		NSD3_HUMAN (4-424): 2.23e-79: 290: 17.79
+	Hs
		355534 H31T_HUMAN (1-132): 8.8e-57: 174: 93.18		NSD2_HUMAN (4-411): 3.14e-80: 292: 17.44
+	Hs
		355545 H32_HUMAN (1-132): 1.31e-56: 174: 96.97		NSD2_HUMAN (4-411): 3.14e-80: 292: 17.44
+	Hs
		1017187 H33_HUMAN (1-132): 3.67e-57: 175: 100.00		NSD3_HUMAN (4-424): 2.23e-79: 290: 17.79
+	Hs
		1162034 H31T_HUMAN (1-132): 8.8e-57: 174: 93.18		NSD3_HUMAN (4-424): 2.23e-79: 290: 17.79
+	Hs
		1239475 H3C_HUMAN (1-132): 2.18e-54: 168: 95.46		NSD3_HUMAN (4-424): 2.23e-79: 290: 17.79
+	Hs
		355456 CENPA_HUMAN (9-132): 4.71e-44: 142: 50.38		NSD2_HUMAN (4-411): 3.14e-80: 292: 17.44
+	Hs
		883678 CENPA_HUMAN (9-132): 4.71e-44: 142: 50.38		NSD3_HUMAN (4-424): 2.23e-79: 290: 17.79