HitPredict

Interactor 1: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Interactor 2: YTHD3 (Q7Z739)
YTH domain-containing family protein 3 (DF3)
Gene: YTHDF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	29395067, 34133714
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule GO:0045727 - positive regulation of translation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 585
+	Hs
		1174879 LARP4_HUMAN (1-724): 9.66e-130: 403: 100.00		YTHD2_HUMAN (1-581): 6.75e-156: 460: 65.81
+	Hs
		1174847 LARP4_HUMAN (1-724): 9.66e-130: 403: 100.00		YTHD1_HUMAN (1-570): 2.77e-137: 412: 66.55
+	Hs
		1192346 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		YTHD3_HUMAN (1-568): 2.64e-171: 500: 100.00
+	Hs
		1268204 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		YTHD2_HUMAN (1-581): 6.75e-156: 460: 65.81
+	Hs
		1268159 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		YTHD1_HUMAN (1-570): 2.77e-137: 412: 66.55
+	At
		1275967 LRP1A_ARATH (88-229): 3e-29: 126: 30.07		Q9FPE7_ARATH (170-579): 6.29e-114: 351: 29.98
+	Hs
		1268147 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		YTDC1_HUMAN (327-581): 1.19e-53: 196: 18.38
+	Hs
		1116549 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		YTDC2_HUMAN (286-551): 2.37e-57: 210: 21.61
+	Hs
		1116465 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		YTDC1_HUMAN (327-581): 1.19e-53: 196: 18.38
+	Mm
		1351630 PCLO_MOUSE (286-724): 1.46e-15: 83.4: 9.80		PCLO_MOUSE (119-407): 5.35e-13: 74.6: 15.20
+	Dm
		113976 M9PB30_DROME (372-722): 4.67e-09: 62.2: 9.01		M9PB30_DROME (178-413): 2.34e-10: 66.1: 11.62