HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IQ~Myosin_head, Myosin_head~Myosin_head, Myosin_head~Myosin_tail_1
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016020 - membrane GO:0051015 - actin filament binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 2054
+	Hs
		214633 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		1268124 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		117614 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		117872 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84
+	Hs
		528356 MYH6_HUMAN (4-1060): 0: 1050: 26.70		MYH6_HUMAN (1141-2053): 1.27e-51: 204: 13.34
+	Hs
		502901 MYH6_HUMAN (4-1060): 0: 1050: 26.70		MYH3_HUMAN (1134-2052): 4.44e-51: 202: 15.52
+	Hs
		528432 MYH8_HUMAN (5-1047): 0: 1039: 26.26		MYH13_HUMAN (1051-1986): 4.14e-54: 212: 13.75
+	Hs
		214519 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		522585 MYH7_HUMAN (4-1060): 0: 1068: 27.29		MYH7_HUMAN (954-1819): 2.95e-41: 169: 12.80
+	Hs
		725086 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Rn
		361106 MYH6_RAT (4-1060): 0: 1057: 26.79		MYH6_RAT (956-1858): 6.36e-41: 168: 13.00
+	Hs
		522657 MYH7_HUMAN (4-1060): 0: 1068: 27.29		MYH4_HUMAN (976-1822): 6.83e-37: 155: 13.06
+	Hs
		502933 MYH3_HUMAN (5-1045): 0: 1044: 26.86		MYH4_HUMAN (976-1822): 6.83e-37: 155: 13.06
+	Zm
		41368 A0A1D6NKQ5_MAIZE (10-1040): 0: 1129: 30.08		A0A1D6NKQ5_MAIZE (1408-1684): 1.98e-09: 65.2: 8.93
+	At
		1107099 MYO5_ARATH (10-1061): 0: 1113: 30.53		MYO5_ARATH (1611-1865): 1.11e-09: 65.9: 10.90
+	Hs
		214675 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		MYO5C_HUMAN (1119-1615): 4.36e-24: 113: 12.21
+	Zm
		21849 A0A1D6HXR0_MAIZE (10-1040): 0: 1105: 29.83		A0A1D6HXR0_MAIZE (1738-1914): 1.56e-09: 65.5: 17.42
+	Mm
		1303337 MYO5A_MOUSE (11-1020): 0: 1049: 29.02		MYO5A_MOUSE (1600-2052): 2.08e-24: 114: 12.04
+	Hs
		1343920 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		MYO5C_HUMAN (1119-1615): 4.36e-24: 113: 12.21