HitPredict

Interactor 1: M9MRE1 (M9MRE1)
PDGF- and VEGF-receptor related, isoform K (EC 2.7.10.1)
Gene: Pvr

Interactor 2: CRK (Q9XYM0)
Adapter molecule Crk
Gene: CRK

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	15457211
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1500 Dm			1 271
+	Dm
		117927 M9MRE1_DROME (19-1500): 0: 983: 100.00		Q9VXH3_DROME (5-267): 3.06e-35: 135: 15.16
+	Dm
		117901 M9MRE1_DROME (19-1500): 0: 983: 100.00		GRAP_DROME (109-257): 4.27e-21: 90.2: 16.35
+	Hs
		786982 FLT3_HUMAN (210-1297): 1.92e-163: 521: 19.35		CRK_HUMAN (4-266): 6.15e-53: 176: 42.48
+	Hs
		786983 FLT3_HUMAN (210-1297): 1.92e-163: 521: 19.35		CRKL_HUMAN (4-267): 9.7e-53: 175: 42.72
+	Hs
		787001 FLT3_HUMAN (210-1297): 1.92e-163: 521: 19.35		GRB2_HUMAN (205-256): 1.68e-13: 69.7: 28.30
+	Hs
		463008 FLT3_HUMAN (210-1297): 1.92e-163: 521: 19.35		YES_HUMAN (12-93): 2.11e-09: 59.7: 39.54
+	Hs
		609961 VGFR1_HUMAN (8-674): 6.43e-61: 232: 12.34		CRKL_HUMAN (4-267): 9.7e-53: 175: 42.72
+	Hs
		609948 VGFR1_HUMAN (8-674): 6.43e-61: 232: 12.34		PLCG1_HUMAN (2-269): 1.77e-39: 147: 15.89
+	Mm
		641293 FGFR2_MOUSE (3-397): 1.23e-53: 205: 12.02		CRKL_MOUSE (4-267): 1.64e-52: 174: 42.38
+	Hs
		618973 FGFR2_HUMAN (3-366): 6.45e-57: 215: 11.17		PLCG1_HUMAN (2-269): 1.77e-39: 147: 15.89
+	Mm
		313427 KIT_MOUSE (42-594): 1.02e-48: 191: 16.87		GRAP2_MOUSE (4-258): 1.3e-41: 147: 15.58
+	Hs
		292800 CSF1R_HUMAN (44-562): 4.45e-50: 195: 13.80		GRAP2_HUMAN (4-258): 6.74e-39: 140: 17.31
+	Hs
		292803 KIT_HUMAN (26-566): 8.74e-47: 185: 18.12		GRAP2_HUMAN (4-258): 6.74e-39: 140: 17.31
+	Hs
		641273 FGFR2_HUMAN (3-366): 6.45e-57: 215: 11.17		ITSN2_HUMAN (164-269): 2.54e-15: 77.8: 14.82
+	Hs
		462979 VGFR1_HUMAN (8-674): 6.43e-61: 232: 12.34		YES_HUMAN (12-93): 2.11e-09: 59.7: 39.54
+	Hs
		641152 FGFR2_HUMAN (3-366): 6.45e-57: 215: 11.17		GRB2_HUMAN (205-256): 1.68e-13: 69.7: 28.30
+	Mm
		431453 KIT_MOUSE (42-594): 1.02e-48: 191: 16.87		VAV_MOUSE (131-257): 4.73e-15: 76.7: 21.09
+	Hs
		456140 CSF1R_HUMAN (44-562): 4.45e-50: 195: 13.80		GRB2_HUMAN (205-256): 1.68e-13: 69.7: 28.30
+	Mm
		431458 KIT_MOUSE (42-594): 1.02e-48: 191: 16.87		GRB2_MOUSE (205-256): 1.75e-13: 69.7: 28.30
+	Hs
		456122 CSF1R_HUMAN (44-562): 4.45e-50: 195: 13.80		YES_HUMAN (12-93): 2.11e-09: 59.7: 39.54