Interactor 1: Q7KY08 (Q7KY08)
Argonaute protein (Argonaute-1, isoform B) (SD07515p)
Gene: AGO1

Interactor 2: DCR1 (Q9VCU9)
Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.3)
Gene: Dcr-1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 15918769
Identification Methods pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArgoL1~PAZ, ArgoL2~PAZ, PAZ~PAZ, PAZ~Ribonuclease_3, PAZ~Piwi
Common GO terms GO:0003727 - single-stranded RNA binding
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007367 - segment polarity determination
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 950
Dm

1 2249
+ Dm
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024