HitPredict

Interactor 1: CEA21 (Q3KPI0)
Cell adhesion molecule CEACAM21 (Carcinoembryonic antigen-related cell adhesion molecule 21) (CEA cell adhesion molecule 21)
Gene: CEACAM21

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2-set_2~Ig_3, Ig_3~V-set, C2-set_2~V-set, V-set~V-set
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 538
+	Hs
		580778 CEA21_HUMAN (1-293): 1.94e-71: 223: 100.00		PVR_HUMAN (25-423): 4.78e-59: 203: 43.92
+	Hs
		1439198 ROBO2_HUMAN (3-250): 4.73e-41: 153: 16.54		ROBO1_HUMAN (37-532): 4.85e-54: 199: 12.60
+	Hs
		320888 LRIG1_HUMAN (12-289): 1.23e-45: 166: 15.14		LRIG2_HUMAN (161-392): 1.55e-32: 135: 16.19
+	Hs
		1101731 CEA21_HUMAN (1-293): 1.94e-71: 223: 100.00		PTK7_HUMAN (263-483): 1.84e-13: 75.5: 15.45
+	Hs
		1491858 ROBO1_HUMAN (138-282): 6.62e-22: 97.6: 16.56		ROBO1_HUMAN (37-532): 4.85e-54: 199: 12.60
+	Hs
		1186216 CEA21_HUMAN (1-293): 1.94e-71: 223: 100.00		CADM4_HUMAN (267-538): 2.28e-12: 70.9: 11.38
+	Ce
		109599 SAX3_CAEEL (145-292): 1.2e-22: 99.9: 15.63		SAX3_CAEEL (33-445): 2.24e-49: 185: 13.51
+	Dm
		233625 O44924_DROME (2-179): 2.74e-16: 81: 12.02		O44924_DROME (29-469): 3.76e-45: 172: 13.33
+	Rn
		236995 DCC_RAT (3-266): 9.73e-19: 88.3: 9.71		ROBO1_RAT (27-360): 2.29e-40: 158: 14.58
+	Hs
		71393 HECA2_HUMAN (25-292): 5.11e-47: 165: 20.62		CADM4_HUMAN (267-538): 2.28e-12: 70.9: 11.38
+	Hs
		1439191 ROBO2_HUMAN (3-250): 4.73e-41: 153: 16.54		ROBO2_HUMAN (449-538): 3.83e-09: 61.7: 15.15
+	Hs
		1249978 LRIG3_HUMAN (143-281): 3.4e-14: 74.8: 18.42		LRIG1_HUMAN (153-427): 3.13e-33: 137: 14.14
+	Dm
		1230945 PTK7_DROME (80-286): 4.77e-19: 89: 21.83		PTK7_DROME (163-337): 2.74e-22: 103: 20.88
+	Hs
		249220 ROBO1_HUMAN (138-282): 6.62e-22: 97.6: 16.56		DSCAM_HUMAN (43-532): 1.85e-14: 79: 9.38
+	Mm
		999933 DCC_MOUSE (3-266): 8.05e-18: 85.6: 9.35		DSCAM_MOUSE (43-532): 3.95e-15: 80.9: 9.76
+	Hs
		731840 CEAM8_HUMAN (12-260): 1.23e-19: 89.1: 14.62		PTK7_HUMAN (263-483): 1.84e-13: 75.5: 15.45
+	Dm
		1427747 Q9GPP6_DROME (9-177): 3.22e-10: 62.9: 10.86		Q9GPP6_DROME (24-365): 7.73e-17: 86.3: 10.75
+	Dm
		1483766 Q9VPZ7_DROME (9-177): 3.19e-10: 62.9: 10.86		Q9VPZ7_DROME (24-365): 7.53e-17: 86.3: 10.75