HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: WDR59 (Q8C0M0)
GATOR2 complex protein WDR59 (CUL4- and DDB1-associated WDR protein 12) (WD repeat-containing protein 59)
Gene: WDR59

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MMS1_N~WD40, CPSF_A~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Mm			1 992
+	Hs
		1147922 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		WDR59_HUMAN (1-992): 0: 780: 94.56
+	Hs
		1157733 DDB1_HUMAN (1-1140): 0: 1445: 99.65		RBBP7_HUMAN (43-334): 9.44e-63: 221: 19.80
+	Hs
		1157912 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL1R_HUMAN (176-533): 2.46e-38: 152: 9.14
+	Mm
		312090 DDB1_MOUSE (1-1140): 0: 1446: 100.00		WDR1_MOUSE (15-318): 9.92e-35: 143: 11.03
+	Hs
		270366 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR1_HUMAN (15-318): 1.58e-32: 136: 11.28
+	Hs
		1157795 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (319-532): 7.31e-24: 105: 10.81
+	Hs
		964975 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (320-532): 1.39e-23: 104: 9.96
+	Hs
		1157890 DDB1_HUMAN (1-1140): 0: 1445: 99.65		GRWD1_HUMAN (96-358): 8.11e-20: 95.7: 15.99
+	Hs
		845309 DDB1_HUMAN (1-1140): 0: 1445: 99.65		LIS1_HUMAN (315-537): 4.22e-19: 93: 8.26
+	Hs
		1066320 DDB1_HUMAN (1-1140): 0: 1445: 99.65		RBBP4_HUMAN (124-361): 4.28e-16: 83.7: 16.72
+	Hs
		1157860 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (359-532): 4.61e-12: 70.6: 8.43
+	At
		198899 DDB1A_ARATH (2-1140): 0: 1254: 52.18		MSI3_ARATH (33-221): 1.18e-21: 101: 15.42
+	At
		198892 DDB1A_ARATH (2-1140): 0: 1254: 52.18		MSI1_ARATH (43-221): 3.88e-20: 96.4: 15.57
+	At
		198898 DDB1B_ARATH (3-1140): 0: 1248: 51.00		MSI3_ARATH (33-221): 1.18e-21: 101: 15.42
+	At
		1444136 DDB1A_ARATH (2-1140): 0: 1254: 52.18		HTD1_ARATH (91-368): 9.42e-18: 89.5: 16.67
+	Hs
		1148066 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		NLE1_HUMAN (174-526): 1.36e-66: 233: 10.95
+	At
		846864 DDB1A_ARATH (2-1140): 0: 1254: 52.18		COP1_ARATH (59-218): 6.64e-11: 68.3: 18.13
+	At
		235864 DDB1B_ARATH (3-1140): 0: 1248: 51.00		COP1_ARATH (59-218): 6.64e-11: 68.3: 18.13
+	Hs
		1147988 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FBXW7_HUMAN (139-501): 1.74e-46: 180: 11.17
+	Hs
		1148022 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		GRWD1_HUMAN (96-358): 8.11e-20: 95.7: 15.99