HitPredict

Interactor 1: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26841866, 24981860, 23752268
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1322 Hs			1 488
+	Hs
		1038491 EMSY_HUMAN (1-1322): 5.68e-132: 441: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Dm
		1276550 Q9VQ58_DROME (4-1041): 9e-37: 153: 15.74		HDAC1_DROME (5-472): 0: 653: 77.92
+	Hs
		1192146 HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038652 MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		152639 KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1056969 MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40