HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: FBLN1 (P23142)
Fibulin-1 (FIBL-1)
Gene: FBLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0010628 - positive regulation of gene expression GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 703
+	Hs
		119465 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		SORL_HUMAN (28-425): 1.44e-21: 102: 13.47
+	Hs
		121199 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		SORL_HUMAN (28-425): 1.44e-21: 102: 13.47
+	Mm
		1207904 Q8C253_MOUSE (5-146): 1.36e-40: 145: 36.24		CUBN_MOUSE (7-263): 5.52e-21: 100: 15.27
+	Hs
		449244 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		NOTC2_HUMAN (265-642): 2.76e-25: 114: 16.43
+	Hs
		449330 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		SORL_HUMAN (28-425): 1.44e-21: 102: 13.47
+	Hs
		449220 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		NOTC1_HUMAN (360-662): 1.29e-18: 93.1: 15.16
+	Hs
		449241 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		JAG1_HUMAN (294-645): 3.52e-18: 91.6: 12.77
+	Hs
		449390 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		JAG2_HUMAN (1-414): 1.1e-17: 90: 13.64
+	Hs
		449386 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		NOTC3_HUMAN (403-663): 1e-14: 80.8: 15.30
+	Hs
		449369 LEG1_HUMAN (234-353): 8.36e-34: 123: 32.00		TEN3_HUMAN (480-665): 3.23e-12: 72.3: 10.66