HitPredict

Interactor 1: Q49AR9 (Q49AR9)
ANKS1A protein
Gene: ANKS1A

Interactor 2: DOK3 (Q7L591)
Docking protein 3 (Downstream of tyrosine kinase 3)
Gene: DOK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 570 Hs			1 496
+	Hs
		1272288 ANS1A_HUMAN (1-493): 8.72e-149: 458: 92.90		DOK3_HUMAN (1-496): 0: 539: 100.00
+	Hs
		1272287 SHC3_HUMAN (204-540): 2.05e-48: 179: 16.71		DOK3_HUMAN (1-496): 0: 539: 100.00
+	Rn
		266626 SHC3_RAT (204-541): 1.45e-49: 182: 16.00		DOK1_RAT (60-490): 3.33e-127: 380: 29.61
+	Rn
		1196021 SHC1_RAT (216-570): 7.85e-50: 180: 15.11		DOK1_RAT (60-490): 3.33e-127: 380: 29.61
+	Hs
		711402 SHC1_HUMAN (146-570): 9.13e-51: 185: 13.81		DOK1_HUMAN (60-491): 1.13e-123: 371: 29.92
+	Hs
		772474 NUMB_HUMAN (235-541): 6.04e-61: 214: 15.22		IRS1_HUMAN (65-494): 2.87e-88: 296: 15.58
+	Mm
		772549 SHC1_MOUSE (146-570): 1.17e-53: 193: 13.92		IRS1_MOUSE (65-494): 2.13e-87: 293: 15.32
+	Hs
		160422 SHC1_HUMAN (146-570): 9.13e-51: 185: 13.81		IRS4_HUMAN (65-427): 3.02e-89: 298: 15.90
+	Hs
		249723 SHC1_HUMAN (146-570): 9.13e-51: 185: 13.81		DOK2_HUMAN (61-455): 2.11e-95: 296: 34.04
+	Hs
		220229 NUMB_HUMAN (235-541): 6.04e-61: 214: 15.22		FRS3_HUMAN (198-454): 5.11e-51: 182: 20.58