HitPredict

Interactor 1: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1, Ank_2~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1134 Hs			1 639
+	Hs
		1366018 ANS1A_HUMAN (1-1134): 0: 772: 100.00		SH3K1_HUMAN (1-638): 4.71e-90: 295: 31.85
+	Hs
		1280000 ANS1B_HUMAN (1-1101): 0: 565: 33.44		CD2AP_HUMAN (1-639): 1.27e-133: 407: 100.00
+	Hs
		250305 ANS1A_HUMAN (1-1134): 0: 772: 100.00		VINEX_HUMAN (163-343): 1.32e-12: 72.7: 18.18
+	Mm
		1296729 ANS1B_MOUSE (1-1133): 0: 594: 33.73		SRGP2_MOUSE (2-450): 1.16e-40: 161: 11.82
+	Hs
		222130 ANS1B_HUMAN (1-1101): 0: 565: 33.44		NCK2_HUMAN (2-361): 1.15e-52: 187: 15.86
+	Mm
		1296751 ANS1B_MOUSE (1-1133): 0: 594: 33.73		ARHG7_MOUSE (70-619): 1.16e-33: 139: 13.54
+	Mm
		1296766 ANS1B_MOUSE (1-1133): 0: 594: 33.73		ITSN1_MOUSE (162-599): 7.57e-20: 96.9: 13.60
+	Hs
		1193622 Q49AR9_HUMAN (675-1134): 1.32e-111: 361: 92.70		SH3K1_HUMAN (1-638): 4.71e-90: 295: 31.85
+	Hs
		1360325 CSKI2_HUMAN (1-592): 5.15e-68: 252: 24.96		SH3K1_HUMAN (1-638): 4.71e-90: 295: 31.85
+	Ce
		711465 Q93203_CAEEL (4-1064): 1.57e-93: 327: 15.60		SEM5_CAEEL (2-176): 2.22e-36: 138: 18.92
+	Hs
		222165 CSKI2_HUMAN (1-592): 5.15e-68: 252: 24.96		NCK2_HUMAN (2-361): 1.15e-52: 187: 15.86
+	Hs
		250255 Q49AR9_HUMAN (675-1134): 1.32e-111: 361: 92.70		VINEX_HUMAN (163-343): 1.32e-12: 72.7: 18.18
+	Ce
		1372518 Q93203_CAEEL (4-1064): 1.57e-93: 327: 15.60		Q9U2T9_CAEEL (168-359): 1.77e-11: 69.6: 18.04
+	Hs
		594061 CSKI2_HUMAN (1-592): 5.15e-68: 252: 24.96		NCK1_HUMAN (113-396): 2.7e-26: 113: 14.38
+	Hs
		1154121 MIB1_HUMAN (3-343): 1.55e-41: 168: 22.32		ITSN1_HUMAN (2-336): 1.35e-45: 176: 19.76
+	Hs
		987550 ANK2_HUMAN (213-788): 7.76e-22: 105: 13.07		GRB2_HUMAN (2-168): 2.29e-41: 151: 18.06
+	Hs
		274251 ANR17_HUMAN (2-106): 2.01e-14: 81: 23.81		ITSN2_HUMAN (2-336): 7.69e-44: 171: 18.29
+	Dm
		1467302 TNKS_DROME (147-289): 4.12e-10: 66.2: 35.86		Q9VA36_DROME (4-346): 7.72e-44: 170: 28.12
+	Hs
		1216068 MIB1_HUMAN (3-343): 1.55e-41: 168: 22.32		SPD2A_HUMAN (61-291): 1.07e-09: 63.7: 13.50
+	Hs
		593966 ANK2_HUMAN (213-788): 7.76e-22: 105: 13.07		NCK1_HUMAN (113-396): 2.7e-26: 113: 14.38