HitPredict

Interactor 1: FILA2 (Q5D862)
Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin)
Gene: FLG2

Interactor 2: SH23A (Q9BRG2)
SH2 domain-containing protein 3A (Novel SH2-containing protein 1)
Gene: SH2D3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2391 Hs			1 576
+	Hs
		445059 S10A9_HUMAN (1-109): 6.69e-43: 154: 30.91		SH23A_HUMAN (1-576): 0: 639: 100.00
+	Hs
		682590 S100P_HUMAN (1-95): 4.71e-43: 154: 41.05		SH23A_HUMAN (1-576): 0: 639: 100.00
+	Hs
		424257 S10A8_HUMAN (1-95): 7.66e-36: 133: 29.47		SH23A_HUMAN (1-576): 0: 639: 100.00
+	Hs
		635627 FILA_HUMAN (85-1521): 5.63e-26: 120: 15.64		SH23A_HUMAN (1-576): 0: 639: 100.00
+	Hs
		161389 KMT2D_HUMAN (388-2260): 3.65e-79: 295: 7.20		ABL1_HUMAN (3-223): 5.81e-48: 182: 18.34
+	Hs
		775496 NU214_HUMAN (231-1142): 1.63e-57: 224: 17.35		TEC_HUMAN (3-255): 1.65e-46: 174: 14.02
+	Hs
		407569 S100B_HUMAN (1-92): 1.57e-44: 158: 36.96		SRC_HUMAN (3-256): 3.18e-61: 213: 12.36
+	Hs
		1054123 HORN_HUMAN (491-2391): 2.48e-36: 154: 24.26		BTK_HUMAN (3-255): 1.91e-46: 174: 12.59
+	Hs
		444948 S10A9_HUMAN (1-109): 6.69e-43: 154: 30.91		GRB2_HUMAN (3-166): 1.35e-44: 159: 19.21
+	Hs
		424172 S10A8_HUMAN (1-95): 7.66e-36: 133: 29.47		GRB2_HUMAN (3-166): 1.35e-44: 159: 19.21
+	Hs
		445159 S10A6_HUMAN (3-91): 1.5e-34: 130: 30.34		GRB2_HUMAN (3-166): 1.35e-44: 159: 19.21
+	Hs
		444905 S10A9_HUMAN (1-109): 6.69e-43: 154: 30.91		SHC1_HUMAN (1-117): 5.11e-32: 132: 32.26
+	Hs
		424140 S10A8_HUMAN (1-95): 7.66e-36: 133: 29.47		SHC1_HUMAN (1-117): 5.11e-32: 132: 32.26
+	Hs
		445131 S10A6_HUMAN (3-91): 1.5e-34: 130: 30.34		SHC1_HUMAN (1-117): 5.11e-32: 132: 32.26