HitPredict

Interactor 1: MD12L (Q86YW9)
Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like)
Gene: MED12L

Interactor 2: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20467437
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2145 Hs			1 802
+	Hs
		1274335 MED12_HUMAN (1-2036): 0: 2238: 58.62		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		1303723 WDR33_HUMAN (1582-2011): 1.04e-17: 92.7: 9.79		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		999006 EP300_HUMAN (1799-2145): 2.26e-11: 71.9: 11.05		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		867120 SC24C_HUMAN (1976-2145): 7.55e-09: 63.3: 15.29		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		486899 EP300_HUMAN (1799-2145): 2.26e-11: 71.9: 11.05		MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51
+	Hs
		486837 CHD7_HUMAN (1582-2128): 8.44e-26: 119: 12.41		MYB_HUMAN (398-727): 5.82e-27: 119: 12.06
+	Hs
		486810 KMT2E_HUMAN (1557-2020): 2.36e-16: 88: 10.32		MYB_HUMAN (398-727): 5.82e-27: 119: 12.06
+	Hs
		486778 EP300_HUMAN (1799-2145): 2.26e-11: 71.9: 11.05		MYB_HUMAN (398-727): 5.82e-27: 119: 12.06