HitPredict

Interactor 1: KSR1 (Q8IVT5)
Kinase suppressor of Ras 1 (EC 2.7.11.1)
Gene: KSR1

Interactor 2: NGAP (Q9UJF2)
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)
Gene: RASAL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 923 Hs			1 1139
+	Hs
		1072624 EPHA7_HUMAN (215-914): 9.83e-149: 467: 14.59		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		411884 LCK_HUMAN (591-890): 2.14e-99: 322: 24.59		NGAP_HUMAN (1-1139): 0: 1051: 100.00
+	Hs
		872693 EPHA4_HUMAN (206-912): 6.5e-164: 506: 14.77		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		872472 EPHA5_HUMAN (223-888): 4.57e-149: 469: 14.15		SYGP1_HUMAN (2-1138): 0: 765: 43.10
+	Hs
		598496 KSR1_HUMAN (1-923): 0: 765: 100.00		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Hs
		596384 EPHA4_HUMAN (206-912): 6.5e-164: 506: 14.77		RASA1_HUMAN (91-623): 3.64e-142: 457: 26.50
+	Hs
		374193 RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03		IQGA2_HUMAN (87-757): 1.71e-150: 491: 14.63
+	Hs
		596362 EPHB2_HUMAN (223-895): 5.19e-149: 469: 14.82		RASA1_HUMAN (91-623): 3.64e-142: 457: 26.50
+	Hs
		596361 EPHA2_HUMAN (223-917): 2.52e-144: 454: 14.62		RASA1_HUMAN (91-623): 3.64e-142: 457: 26.50
+	Mm
		655985 BRAF_MOUSE (252-914): 2.44e-148: 458: 22.95		IQGA1_MOUSE (126-751): 1.8e-133: 446: 12.33
+	Hs
		542837 BRAF_HUMAN (252-914): 2.03e-148: 459: 22.80		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		596383 EPHB3_HUMAN (193-914): 1.2e-139: 443: 15.58		RASA1_HUMAN (91-623): 3.64e-142: 457: 26.50
+	Mm
		101497 BRAF_MOUSE (252-914): 2.44e-148: 458: 22.95		F8VQ29_MOUSE (127-711): 7.84e-132: 441: 12.89
+	Hs
		373859 RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03		IQGA1_HUMAN (88-751): 2.04e-132: 443: 12.10
+	Hs
		411591 LCK_HUMAN (591-890): 2.14e-99: 322: 24.59		RASA1_HUMAN (91-623): 3.64e-142: 457: 26.50
+	Hs
		598429 EPHA2_HUMAN (223-917): 2.52e-144: 454: 14.62		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Hs
		373677 RAF1_HUMAN (229-908): 9.62e-143: 440: 22.03		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Hs
		598423 EPHA1_HUMAN (223-917): 1.29e-138: 439: 15.72		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17
+	Hs
		411593 LCK_HUMAN (591-890): 2.14e-99: 322: 24.59		NF1_HUMAN (293-621): 8.74e-89: 317: 26.17