HitPredict

Interactor 1: GCC2 (Q8IWJ2)
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Gene: GCC2

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709727
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1684 Hs			1 805
+	Hs
		725237 MYH10_HUMAN (697-1684): 5.34e-42: 171: 9.78		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1061234 NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1034622 GOGA4_HUMAN (1-1028): 1.78e-31: 137: 12.68		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		725001 MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Hs
		1059264 GOGB1_HUMAN (1285-1677): 1.11e-09: 66.1: 12.44		ACE2_HUMAN (12-805): 0: 1184: 100.00
+	Mm
		450972 MYH9_MOUSE (1-933): 3.94e-38: 159: 11.75		ACE_MOUSE (19-661): 0: 818: 38.74
+	Hs
		521667 MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41		ACE_HUMAN (19-662): 0: 812: 39.91