HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	10339433
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 518
+	Hs
		584401 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		RIPK1_HUMAN (21-288): 1.18e-33: 137: 33.90
+	Hs
		201753 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		RIPK2_HUMAN (14-291): 6.42e-33: 133: 32.32
+	Mm
		626861 TNR1A_MOUSE (1-445): 4.25e-127: 377: 64.37		RIPK1_MOUSE (15-276): 9.95e-36: 142: 34.39
+	Hs
		154359 TR10B_HUMAN (31-445): 1.86e-78: 252: 19.81		RIPK1_HUMAN (21-288): 1.18e-33: 137: 33.90
+	Hs
		1038297 TNR25_HUMAN (39-442): 1.12e-77: 249: 27.36		RIPK1_HUMAN (21-288): 1.18e-33: 137: 33.90
+	Hs
		632270 TNR6_HUMAN (1-167): 7.65e-47: 166: 23.21		RIPK1_HUMAN (21-288): 1.18e-33: 137: 33.90
+	Hs
		591326 TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86		RIPK1_HUMAN (21-288): 1.18e-33: 137: 33.90
+	Hs
		201756 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		RIPK2_HUMAN (14-291): 6.42e-33: 133: 32.32
+	Mm
		812914 TNR4_MOUSE (52-252): 2.35e-32: 125: 17.91		RIPK1_MOUSE (15-276): 9.95e-36: 142: 34.39
+	Hs
		201745 TNR16_HUMAN (40-303): 1.33e-29: 121: 18.46		RIPK2_HUMAN (14-291): 6.42e-33: 133: 32.32