HitPredict

Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: SRS12 (Q8WXF0)
Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)
Gene: SRSF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1101 Hs			1 261
+	Hs
		267020 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Hs
		1221594 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		PPIL4_HUMAN (6-254): 6.19e-32: 124: 17.32
+	Hs
		952028 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		964023 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		SRSF2_HUMAN (4-90): 1.12e-22: 94.6: 45.65
+	Hs
		1031385 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		PABP4_HUMAN (2-101): 2.19e-20: 92.1: 18.00
+	Hs
		516583 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		1221731 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		PABP3_HUMAN (2-101): 1.25e-17: 84: 16.00
+	Hs
		963547 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		TIAR_HUMAN (4-98): 1.93e-17: 82.5: 16.84
+	Hs
		1084329 SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00		SRSF7_HUMAN (1-108): 2.53e-09: 58.2: 35.78
+	Hs
		1357565 SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Sc
		376836 SMC3_YEAST (51-1055): 7.78e-71: 260: 13.66		PABP_YEAST (2-98): 1.48e-20: 92.5: 22.68