HitPredict

Interactor 1: BCAR1 (Q61140)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas)
Gene: BCAR1

Interactor 2: SOCS6 (Q9JLY0)
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)
Gene: SOCS6

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24284072
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 874 Mm			1 533
+	Rn
		1224621 BCAR1_RAT (4-874): 2.91e-127: 408: 96.90		SRC_RAT (248-493): 5.67e-58: 203: 15.63
+	Mm
		431351 BCAR1_MOUSE (1-874): 8e-129: 410: 100.00		SRC_MOUSE (248-493): 2.62e-56: 198: 15.63
+	Hs
		473388 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		HCK_HUMAN (234-493): 8.77e-59: 205: 15.30
+	Mm
		813523 BCAR1_MOUSE (1-874): 8e-129: 410: 100.00		FYN_MOUSE (258-504): 7.97e-55: 195: 14.06
+	Rn
		1224292 BCAR1_RAT (4-874): 2.91e-127: 408: 96.90		FYN_RAT (258-504): 7.97e-55: 195: 14.06
+	Hs
		440468 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		FYN_HUMAN (258-504): 7.97e-55: 195: 14.06
+	Hs
		557192 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		SRC_HUMAN (256-493): 1.52e-54: 194: 14.92
+	Mm
		683100 BCAR1_MOUSE (1-874): 8e-129: 410: 100.00		LYN_MOUSE (279-493): 1.73e-50: 182: 17.02
+	Hs
		463036 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		YES_HUMAN (318-493): 3.17e-53: 190: 15.14
+	Hs
		440009 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		LCK_HUMAN (260-493): 9.98e-53: 188: 17.21
+	Hs
		463425 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		LYN_HUMAN (279-493): 2.86e-50: 181: 16.60
+	Hs
		440558 CASL_HUMAN (1-872): 1.54e-117: 379: 35.34		FYN_HUMAN (258-504): 7.97e-55: 195: 14.06
+	Hs
		440075 CASL_HUMAN (1-872): 1.54e-117: 379: 35.34		LCK_HUMAN (260-493): 9.98e-53: 188: 17.21
+	Hs
		463518 CASL_HUMAN (1-872): 1.54e-117: 379: 35.34		LYN_HUMAN (279-493): 2.86e-50: 181: 16.60
+	Rn
		1224620 BCAR1_RAT (4-874): 2.91e-127: 408: 96.90		P85A_RAT (382-494): 1.24e-12: 72.4: 23.89
+	Hs
		593951 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		NCK1_HUMAN (203-374): 1.4e-15: 80.3: 13.64
+	Hs
		699667 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		P85A_HUMAN (382-494): 6.55e-13: 73.6: 23.89
+	Hs
		222046 BCAR1_HUMAN (1-874): 2.43e-125: 400: 90.16		NCK2_HUMAN (220-381): 3.16e-12: 70.3: 13.45
+	Hs
		593997 CASL_HUMAN (1-872): 1.54e-117: 379: 35.34		NCK1_HUMAN (203-374): 1.4e-15: 80.3: 13.64
+	Hs
		1127361 CASL_HUMAN (1-872): 1.54e-117: 379: 35.34		P55G_HUMAN (382-503): 9.23e-15: 78.6: 27.05