Interactor 1: DNM1L (Q8K1M6)
Dynamin-1-like protein (EC 3.6.5.5) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1)
Gene: DNM1L

Interactor 2: DNM1L (Q8K1M6)
Dynamin-1-like protein (EC 3.6.5.5) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1)
Gene: DNM1L

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 20585624, 24508339, 30914652
Identification Methods two hybrid, transmission electron microscopy, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynamin_M~Dynamin_M, Dynamin_M~Dynamin_N, Dynamin_M~GED, Dynamin_N~Dynamin_N, GED~GED
Common GO terms GO:0000139 - Golgi membrane
GO:0000266 - mitochondrial fission
GO:0001836 - release of cytochrome c from mitochondria
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
and 64 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 736
Mm

1 736
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ At
+ Sc
+ At
+ At
+ At
+ At

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Last updated: 15 Jul 2024