HitPredict

Interactor 1: NUP98 (Q6PFD9)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Interactor 2: RAE1L (Q8C570)
mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41)
Gene: Rae1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30683868
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Nup96~WD40, Nup98_GLEBS~WD40
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1816 Mm			1 368
+	Hs
		915943 NUP98_HUMAN (1-1815): 0: 1563: 91.58		RAE1L_HUMAN (1-368): 2.47e-100: 303: 98.64
+	Hs
		915937 NUP98_HUMAN (1-1815): 0: 1563: 91.58		WDR5_HUMAN (261-367): 1.41e-24: 104: 13.89
+	Dm
		1470425 NUP98_DROME (1-1801): 0: 920: 27.55		RAE1_DROME (21-365): 2.26e-81: 253: 68.70
+	Dm
		1463905 NUP98_DROME (1-1801): 0: 920: 27.55		WDS_DROME (73-368): 1.7e-72: 231: 14.47
+	Ce
		112531 NUP98_CAEEL (1-1722): 0: 806: 22.72		BUB3_CAEEL (30-365): 5.11e-89: 273: 27.86
+	Hs
		775520 NU214_HUMAN (2-595): 2.15e-20: 101: 14.68		RAE1L_HUMAN (1-368): 2.47e-100: 303: 98.64
+	Hs
		890300 NU153_HUMAN (2-231): 4.25e-09: 64: 16.88		RAE1L_HUMAN (1-368): 2.47e-100: 303: 98.64
+	Sc
		817848 NU116_YEAST (61-739): 1.63e-22: 107: 16.28		GLE2_YEAST (1-368): 4.09e-81: 253: 40.43
+	Dm
		1482052 Q9VMV5_DROME (3-462): 1.14e-20: 102: 10.43		RAE1_DROME (21-365): 2.26e-81: 253: 68.70
+	Xl
		1231399 Q6DCP4_XENLA (82-660): 2.81e-10: 67.5: 12.33		Q7ZZY7_XENLA (24-368): 2.41e-92: 282: 92.75
+	Sc
		817836 NU159_YEAST (345-740): 3.21e-16: 87.5: 13.30		GLE2_YEAST (1-368): 4.09e-81: 253: 40.43
+	Sc
		817847 NU100_YEAST (191-764): 1.38e-13: 78.7: 15.56		GLE2_YEAST (1-368): 4.09e-81: 253: 40.43
+	Sc
		817840 NUP57_YEAST (2-197): 7.54e-12: 72: 28.13		GLE2_YEAST (1-368): 4.09e-81: 253: 40.43
+	Sc
		577307 NSP1_YEAST (142-713): 1.17e-09: 65.5: 16.35		GLE2_YEAST (1-368): 4.09e-81: 253: 40.43
+	At
		100707 NU98B_ARATH (2-890): 1.82e-42: 172: 17.56		RAE1_ARATH (14-200): 3.71e-15: 77.4: 11.71
+	At
		1182574 NU98A_ARATH (109-755): 2.72e-17: 90.6: 13.96		RAE1_ARATH (14-200): 3.71e-15: 77.4: 11.71
+	Hs
		245721 GANP_HUMAN (192-639): 1.18e-11: 72.5: 14.07		POC1A_HUMAN (258-342): 2.19e-17: 84.6: 14.12
+	At
		1182598 NUP1_ARATH (2-432): 3.22e-12: 74.3: 17.67		RAE1_ARATH (14-200): 3.71e-15: 77.4: 11.71
+	Hs
		1387488 P121A_HUMAN (43-493): 9.25e-09: 62.8: 20.89		SNR40_HUMAN (2-112): 9.18e-19: 88.1: 19.38