Interactor 1: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Interactor 2: MIOS (Q9NXC5)
GATOR2 complex protein MIOS (Missing oocyte meiosis regulator homolog)
Gene: MIOS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.886

The method score is based on:

Property Details
Experiments 26972053, 28199306, 37689310, 35831510
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MIOS_WD40~WD40, WD40~zinc_ribbon_16, zf-RING_16~zinc_ribbon_16
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0031669 - cellular response to nutrient levels
GO:0034198 - cellular response to amino acid starvation
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 974
Hs

1 875
+ Hs
+ Dm
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+ Dm
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+ Sc
+ Sc
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+ Ce
+ At
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+ Hs
+ Hs
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+ Dm
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+ Hs
+ Hs

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Last updated: 11Aug2025