HitPredict

Interactor 1: WDR5B (Q86VZ2)
WD repeat-containing protein 5B
Gene: WDR5B

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17041588
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042393 - histone binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 446
+	Hs
		965194 WDR5_HUMAN (2-286): 9.24e-96: 288: 29.21		GRWD1_HUMAN (1-446): 1.7e-119: 357: 100.00
+	Hs
		964797 WDR5_HUMAN (2-286): 9.24e-96: 288: 29.21		WDR5_HUMAN (248-445): 1.74e-47: 167: 21.72
+	Hs
		965071 WDR5B_HUMAN (2-282): 1.49e-91: 277: 29.97		WDR5_HUMAN (248-445): 1.74e-47: 167: 21.72
+	Hs
		845264 WDR5_HUMAN (2-286): 9.24e-96: 288: 29.21		LIS1_HUMAN (257-445): 1.64e-41: 153: 17.60
+	Hs
		1410246 TBL1Y_HUMAN (62-330): 4.38e-60: 202: 24.40		TBL1R_HUMAN (46-385): 3.37e-62: 211: 14.47
+	Dm
		1463899 WDS_DROME (2-286): 3.33e-95: 288: 29.90		WDS_DROME (295-445): 5.51e-31: 124: 15.23
+	Hs
		261440 TBL1X_HUMAN (120-330): 5.73e-49: 173: 27.56		TBL1R_HUMAN (46-385): 3.37e-62: 211: 14.47
+	Hs
		964891 WDR5_HUMAN (2-286): 9.24e-96: 288: 29.21		RBBP4_HUMAN (66-247): 7.51e-20: 93.1: 10.42
+	Hs
		965141 FBXW7_HUMAN (2-233): 2.06e-62: 212: 25.52		WDR5_HUMAN (248-445): 1.74e-47: 167: 21.72
+	Hs
		965276 WDR5_HUMAN (2-286): 9.24e-96: 288: 29.21		NLE1_HUMAN (338-445): 3.35e-17: 85.8: 13.89
+	Hs
		965034 WDR5_HUMAN (2-286): 9.24e-96: 288: 29.21		WDR59_HUMAN (259-382): 1.25e-12: 72: 28.23
+	Hs
		209230 PRP4_HUMAN (125-330): 5.04e-50: 175: 22.43		WDR5_HUMAN (248-445): 1.74e-47: 167: 21.72
+	Ce
		1018728 LIS1_CAEEL (2-240): 4.45e-73: 232: 27.06		LIN53_CAEEL (41-247): 1.43e-20: 95.4: 10.33
+	Hs
		1334151 POC1B_HUMAN (154-330): 4.91e-47: 167: 20.90		POC1A_HUMAN (56-335): 1.63e-40: 151: 12.81
+	Hs
		222461 PLRG1_HUMAN (158-328): 2.45e-40: 149: 28.66		WDR5_HUMAN (248-445): 1.74e-47: 167: 21.72
+	Hs
		1158951 FBXW7_HUMAN (2-233): 2.06e-62: 212: 25.52		RBBP7_HUMAN (66-247): 3.47e-20: 94.2: 10.42
+	Hs
		261419 TBL1X_HUMAN (120-330): 5.73e-49: 173: 27.56		WDR59_HUMAN (259-382): 1.25e-12: 72: 28.23
+	Hs
		1245330 TBL1R_HUMAN (120-330): 2.48e-48: 171: 28.00		WDR59_HUMAN (259-382): 1.25e-12: 72: 28.23
+	Hs
		1450936 NLE1_HUMAN (193-329): 6.49e-33: 128: 22.38		NLE1_HUMAN (338-445): 3.35e-17: 85.8: 13.89