Interactor 1: WDR59 (Q9VKK2)
GATOR2 complex protein Wdr59
Gene: WDR59

Interactor 2: MIO (Q9VQ89)
GATOR2 complex protein Mio (Protein missing oocyte)
Gene: MIO

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 27166823, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MIOS_WD40~WD40, WD40~zinc_ribbon_16, zf-RING_16~zinc_ribbon_16
Common GO terms GO:0008270 - zinc ion binding
GO:0032008 - positive regulation of TOR signaling
GO:0034198 - cellular response to amino acid starvation
GO:0035859 - Seh1-associated complex
GO:0061700 - GATOR2 complex
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 969
Dm

1 867
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+ Dm
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Last updated: 11Aug2025