HitPredict

Interactor 1: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24

Interactor 2: MIOS (Q9NXC5)
GATOR2 complex protein MIOS (Missing oocyte meiosis regulator homolog)
Gene: MIOS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 27173435, 35831510, 23723238, 28199306, 25263562, 28199315, 26449471, 26586190, 26972053
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MIOS_WD40~WD40, WD40~zinc_ribbon_16
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0031669 - cellular response to nutrient levels
GO:0034198 - cellular response to amino acid starvation
and 3 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 790
Hs

1 875
+ Hs
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+ Dm
+ Dm
+ Sc
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+ At
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Service provided by Combinatics, Japan

Last updated: 11Aug2025