HitPredict

Interactor 1: DCA11 (Q8TEB1)
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)
Gene: DCAF11

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31253590, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 546 Hs			1 780
+	Hs
		1042119 DCA11_HUMAN (18-546): 5.28e-125: 379: 100.00		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1043117 DCA11_HUMAN (18-546): 5.28e-125: 379: 100.00		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043471 DCA11_HUMAN (18-546): 5.28e-125: 379: 100.00		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		792982 LIS1_HUMAN (168-471): 3.32e-81: 261: 14.59		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043085 WDR5B_HUMAN (250-544): 2.02e-69: 228: 18.21		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043441 WDR5B_HUMAN (250-544): 2.02e-69: 228: 18.21		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1042655 NLE1_HUMAN (7-335): 7.05e-60: 207: 14.48		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1043562 TBL1R_HUMAN (260-546): 4.79e-66: 224: 14.33		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1043157 SNR40_HUMAN (65-291): 2.25e-44: 162: 12.86		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043509 SNR40_HUMAN (65-291): 2.25e-44: 162: 12.86		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		152875 APAF_HUMAN (72-392): 3.55e-27: 118: 16.31		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042101 POC1B_HUMAN (14-229): 1.27e-26: 114: 10.80		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		197016 PRP4_HUMAN (238-515): 4.91e-26: 113: 14.39		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		154680 GNB5_HUMAN (349-534): 4.65e-28: 117: 16.24		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1043114 POC1B_HUMAN (14-229): 1.27e-26: 114: 10.80		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		152876 APAF_HUMAN (72-392): 3.55e-27: 118: 16.31		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1043469 POC1B_HUMAN (14-229): 1.27e-26: 114: 10.80		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1016274 TBL3_HUMAN (318-546): 1.07e-21: 101: 11.65		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		245601 TBL1X_HUMAN (435-546): 8.58e-14: 76: 11.81		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Sp
		142917 POF11_SCHPO (170-335): 2.38e-13: 74.5: 14.37		CUL1_SCHPO (3-780): 0: 680: 24.97