Protein: MOCS3
Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)]

Gene: MOCS3
Organism: Homo sapiens
Interactions: 53
UniProt ID: O95396

Gene Ontology (top 5):
GO:0002098 - tRNA wobble uridine modification
GO:0002143 - tRNA wobble position uridine thiolation
GO:0004792 - thiosulfate-cyanide sulfurtransferase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335713

SACS
Sacsin

2

0

High-throughput

0.770

High

335702

URM1
Ubiquitin-related modifier 1

1

2

Small-scale

0.710

High

335710

SG196
Protein O-mannose kinase

4

0

High-throughput

0.661

High

335688

HERC4
Probable E3 ubiquitin-protein ligase HERC4

2

11

High-throughput

0.628

High

335704

KLC2
Kinesin light chain 2

2

3

High-throughput

0.628

High

240375

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.618

High

335679

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.618

High

335695

DYHC2
Cytoplasmic dynein 2 heavy chain 1

2

0

High-throughput

0.602

High

335701

FXL18
F-box/LRR-repeat protein 18

2

0

High-throughput

0.602

High

335700

AURKB
Aurora kinase B

1

1

High-throughput

0.575

High

326195

ALX3
Homeobox protein aristaless-like 3

2

2

High-throughput

0.574

High

335686

ISX
Intestine-specific homeobox

2

2

High-throughput

0.549

High

335672

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

335673

HSP76
Heat shock 70 kDa protein 6

1

2

High-throughput

0.536

High

335684

IRF3
Interferon regulatory factor 3

1

2

High-throughput

0.536

High

335699

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

335703

CLPB
Mitochondrial disaggregase

1

4

High-throughput

0.536

High

335717

KLK5
Kallikrein-5

1

2

High-throughput

0.536

High

335678

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

335718

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

231293

EFNA2
Ephrin-A2

1

1

High-throughput

0.489

High

335676

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

335677

I12R1
Interleukin-12 receptor subunit beta-1

1

1

High-throughput

0.489

High

335708

KLK15
Kallikrein-15

1

3

High-throughput

0.489

High

335689

EXOS6
Exosome complex component MTR3

1

1

High-throughput

0.481

High

335692

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

335709

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

335712

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

335715

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

335716

HERC5
E3 ISG15--protein ligase HERC5

1

11

Small-scale

0.479

High

335682

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.470

High

335675

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

335683

NMI
N-myc-interactor

1

0

High-throughput

0.458

High

335714

VSX1
Visual system homeobox 1

1

2

High-throughput

0.437

High

295560

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.426

High

335680

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.426

High

335697

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.426

High

335674

KLK2
Kallikrein-2

1

3

High-throughput

0.407

High

335685

EFNB3
Ephrin-B3

1

1

High-throughput

0.407

High

335691

VASN
Vasorin

1

1

High-throughput

0.407

High

335706

RSPH9
Radial spoke head protein 9 homolog

3

0

High-throughput

0.347

High

335690

LIN9
Protein lin-9 homolog

2

0

High-throughput

0.328

High

231030

VEGFD
Vascular endothelial growth factor D

2

0

High-throughput

0.318

High

335711

CAH10
Carbonic anhydrase-related protein 10

2

0

High-throughput

0.313

High

335687

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.279

Low

335693

BTLA
B- and T-lymphocyte attenuator

1

0

High-throughput

0.279

Low

335696

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

335698

OIT3
Oncoprotein-induced transcript 3 protein

1

0

High-throughput

0.279

Low

335707

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

335705

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.265

Low

335671

INHA
Inhibin alpha chain

1

0

High-throughput

0.232

Low

335681

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

335694

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025