Interactor 1: COX1 (P00395)
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)
Gene: MT-CO1

Interactor 2: COX42 (Q96KJ9)
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (Cytochrome c oxidase subunit IV isoform 2) (COX IV-2)
Gene: COX4I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains COX1~COX4
Common GO terms GO:0004129 - cytochrome-c oxidase activity
GO:0005751 - mitochondrial respiratory chain complex IV
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0045333 - cellular respiration
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 513
Hs

1 171
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024