HitPredict

Interactor 1: SH3R3 (Q8TEJ3)
E3 ubiquitin-protein ligase SH3RF3 (EC 2.3.2.27) (Plenty of SH3s 2) (SH3 domain-containing RING finger protein 3) (SH3 multiple domains protein 4)
Gene: SH3RF3

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 759
+	Hs
		1136557 SPD2A_HUMAN (59-881): 2.54e-21: 102: 10.28		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		299005 SRBS2_HUMAN (523-882): 1.7e-18: 93.2: 14.79		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1045558 SPTN1_HUMAN (652-882): 1.46e-12: 74.1: 13.79		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1355274 PACN3_HUMAN (762-880): 4.09e-10: 65.1: 20.00		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		823431 SH3R1_HUMAN (46-882): 1.03e-98: 330: 42.17		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		1045443 SPTN1_HUMAN (652-882): 1.46e-12: 74.1: 13.79		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		235555 VINEX_HUMAN (686-879): 3.03e-14: 79.1: 20.62		MICA1_HUMAN (333-572): 7.65e-38: 154: 20.00
+	Hs
		1232325 SH3K1_HUMAN (705-882): 2.04e-12: 72.9: 18.23		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		1232326 SH3G1_HUMAN (384-527): 1.07e-11: 69.6: 21.53		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150574 ARHG6_HUMAN (769-882): 3.47e-19: 94.9: 19.30		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		1232342 PACN3_HUMAN (762-880): 4.09e-10: 65.1: 20.00		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Mm
		1113253 SRBS2_MOUSE (286-882): 2.2e-22: 105: 12.62		PAXI_MOUSE (268-446): 9.35e-14: 76.9: 14.53
+	Hs
		823398 ARHG6_HUMAN (769-882): 3.47e-19: 94.9: 19.30		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		823391 ARHG7_HUMAN (829-882): 7.71e-16: 84.1: 37.04		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Mm
		1257659 ARHG7_MOUSE (778-882): 2.26e-14: 79.5: 20.95		PAXI_MOUSE (268-446): 9.35e-14: 76.9: 14.53
+	Hs
		823423 DNMBP_HUMAN (666-881): 2.63e-10: 66.6: 10.22		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		823484 SRBS1_HUMAN (122-250): 1.3e-09: 64.4: 20.61		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		1045413 SPTN1_HUMAN (652-882): 1.46e-12: 74.1: 13.79		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00
+	Dm
		52988 A1Z866_DROME (828-880): 3.46e-11: 68.8: 52.83		MICAL_DROME (371-515): 6.96e-12: 71.8: 24.83