HitPredict

Interactor 1: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 499
+	Hs
		1406176 H2A1J_HUMAN (5-125): 5.91e-56: 172: 62.30		PMYT1_HUMAN (1-499): 4.56e-137: 406: 100.00
+	Hs
		651677 H2AV_HUMAN (1-128): 2.98e-60: 182: 100.00		KAPCB_HUMAN (95-404): 2.52e-126: 373: 21.25
+	Hs
		651705 H2A1A_HUMAN (5-125): 1.01e-56: 174: 62.30		KAPCB_HUMAN (95-404): 2.52e-126: 373: 21.25
+	Hs
		418834 H2A1B_HUMAN (5-125): 4.33e-55: 170: 62.30		KAPCB_HUMAN (95-404): 2.52e-126: 373: 21.25
+	Hs
		501919 H2AZ_HUMAN (1-127): 1.51e-60: 183: 98.43		WEE1_HUMAN (100-359): 5.51e-33: 134: 34.59
+	Hs
		501940 H2AZ_HUMAN (1-127): 1.51e-60: 183: 98.43		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		419145 H2A1B_HUMAN (5-125): 4.33e-55: 170: 62.30		NEK1_HUMAN (108-354): 5.9e-24: 108: 29.57
+	Hs
		909059 H2AV_HUMAN (1-128): 2.98e-60: 182: 100.00		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909145 H2A1A_HUMAN (5-125): 1.01e-56: 174: 62.30		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909016 H2A2C_HUMAN (5-128): 7.11e-56: 172: 62.40		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909079 H2A2B_HUMAN (5-127): 3.97e-56: 172: 60.48		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909157 H2A1J_HUMAN (5-125): 5.91e-56: 172: 62.30		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909167 H2AJ_HUMAN (5-128): 4.16e-56: 172: 60.80		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909139 H2A1H_HUMAN (5-125): 1.37e-55: 171: 62.30		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		419120 H2A1B_HUMAN (5-125): 4.33e-55: 170: 62.30		M4K1_HUMAN (110-362): 2.44e-20: 96.7: 32.21
+	Hs
		418893 H2A1B_HUMAN (5-125): 4.33e-55: 170: 62.30		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		591548 H2AX_HUMAN (5-124): 5.49e-55: 170: 62.81		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		634011 H2A1D_HUMAN (5-125): 3.84e-55: 170: 63.12		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909060 H2A3_HUMAN (5-125): 2.95e-55: 170: 63.12		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65
+	Hs
		909125 H2A1C_HUMAN (5-125): 3.44e-55: 170: 62.30		NEK4_HUMAN (113-361): 3.9e-20: 95.9: 30.65