Protein: PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)

Gene: PMYT1, PKMYT1
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q99640

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000139 - Golgi membrane
GO:0000278 - mitotic cell cycle
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

443491

CDK1
Cyclin-dependent kinase 1

9

20

Small-scale

0.977

High

573880

CCNB1
G2/mitotic-specific cyclin-B1

5

12

Small-scale

0.936

High

629157

CCNA2
Cyclin-A2

5

12

High-throughput

0.932

High

325500

CCNB2
G2/mitotic-specific cyclin-B2

4

12

High-throughput

0.909

High

956684

CKS1
Cyclin-dependent kinases regulatory subunit 1

3

5

High-throughput

0.871

High

753927

CKS2
Cyclin-dependent kinases regulatory subunit 2

4

5

High-throughput

0.813

High

853729

MK08
Mitogen-activated protein kinase 8

1

20

Small-scale

0.756

High

923395

MK10
Mitogen-activated protein kinase 10

1

20

Small-scale

0.756

High

572953

INSRR
Insulin receptor-related protein

1

15

High-throughput

0.691

High

856883

BAG6
Large proline-rich protein BAG6

1

12

High-throughput

0.691

High

977811

ACTA
Actin, aortic smooth muscle

1

20

High-throughput

0.691

High

1140265

IF4H
Eukaryotic translation initiation factor 4H

1

15

High-throughput

0.691

High

1143089

KPCD1
Serine/threonine-protein kinase D1

1

17

High-throughput

0.691

High

212473

SPIT2
Kunitz-type protease inhibitor 2

3

9

High-throughput

0.667

High

253104

PLIN3
Perilipin-3

3

0

High-throughput

0.638

High

665055

IL4RA
Interleukin-4 receptor subunit alpha

2

9

High-throughput

0.628

High

137510

BT3A1
Butyrophilin subfamily 3 member A1

1

5

High-throughput

0.618

High

1406178

EFHD1
EF-hand domain-containing protein D1

1

20

High-throughput

0.618

High

461858

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

820729

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.618

High

901521

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.618

High

920226

PLK1
Serine/threonine-protein kinase PLK1

1

16

High-throughput

0.618

High

1015710

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.618

High

1383029

LRC59
Leucine-rich repeat-containing protein 59

1

6

High-throughput

0.618

High

1395924

DNJC1
DnaJ homolog subfamily C member 1

1

12

High-throughput

0.618

High

1406181

DJC25
DnaJ homolog subfamily C member 25

1

7

High-throughput

0.618

High

1406200

SEC63
Translocation protein SEC63 homolog

1

5

High-throughput

0.618

High

1406201

UBQL2
Ubiquilin-2

1

10

High-throughput

0.618

High

1210299

MF14B
Hippocampus abundant transcript-like protein 1

2

2

High-throughput

0.606

High

1394232

TM101
Transmembrane protein 101

2

1

High-throughput

0.606

High

1406180

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.606

High

1406203

TMX2
Thioredoxin-related transmembrane protein 2

2

5

High-throughput

0.606

High

350407

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.580

High

460277

CD3E
T-cell surface glycoprotein CD3 epsilon chain

2

0

High-throughput

0.580

High

942285

CLD8
Claudin-8

2

0

High-throughput

0.580

High

1236288

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

1291468

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

1310931

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.580

High

1324848

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.580

High

1333268

T229B
Transmembrane protein 229B

2

0

High-throughput

0.580

High

1379870

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.580

High

295625

CIB2
Calcium and integrin-binding family member 2

1

20

High-throughput

0.575

High

1325788

FXL16
F-box/LRR-repeat protein 16

1

9

High-throughput

0.575

High

1406175

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

18

Small-scale

0.575

High

1109365

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

3

Small-scale

0.561

High

951376

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

549867

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.553

High

901005

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.553

High

1225909

STEA3
Metalloreductase STEAP3

1

2

Small-scale

0.552

High

376635

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

420671

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

6

High-throughput

0.536

High

522127

BCL2
Apoptosis regulator Bcl-2

1

5

High-throughput

0.536

High

607411

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

3

High-throughput

0.536

High

699041

CALX
Calnexin

1

2

High-throughput

0.536

High

784837

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

2

High-throughput

0.536

High

935959

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

High-throughput

0.536

High

1008303

PRKDC
DNA-dependent protein kinase catalytic subunit

1

16

High-throughput

0.536

High

1010360

BASP1
Brain acid soluble protein 1

1

5

High-throughput

0.536

High

1101883

SKP2
S-phase kinase-associated protein 2

1

10

High-throughput

0.536

High

1127906

GBX1
Homeobox protein GBX-1

1

7

High-throughput

0.536

High

1163164

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1204068

UROL1
Uromodulin-like 1

1

1

High-throughput

0.536

High

1210512

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

High-throughput

0.536

High

1259631

H2AV
Histone H2A.V

1

20

High-throughput

0.536

High

1370011

GSLG1
Golgi apparatus protein 1

1

2

High-throughput

0.536

High

1383825

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

1392283

ZDH12
Palmitoyltransferase ZDHHC12

1

4

High-throughput

0.536

High

1406176

H2A1J
Histone H2A type 1-J

1

19

High-throughput

0.536

High

1406185

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

1406188

CP26B
Cytochrome P450 26B1

1

1

High-throughput

0.536

High

1406191

SMC4
Structural maintenance of chromosomes protein 4

1

7

High-throughput

0.536

High

1406195

VAPA
Vesicle-associated membrane protein-associated protein A

1

10

High-throughput

0.536

High

1406202

DRG1
Developmentally-regulated GTP-binding protein 1

1

2

High-throughput

0.536

High

1406204

SNX11
Sorting nexin-11

1

4

High-throughput

0.536

High

1406205

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

2

High-throughput

0.536

High

49540

SHSA3
Protein shisa-3 homolog

1

0

High-throughput

0.513

High

214142

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

295866

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.513

High

455855

H10
Histone H1.0

1

0

High-throughput

0.513

High

705527

GRN
Progranulin

1

0

High-throughput

0.513

High

952509

CTXN1
Cortexin-1

1

0

High-throughput

0.513

High

1126346

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1349183

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.513

High

1351510

RNH2C
Ribonuclease H2 subunit C

1

0

High-throughput

0.513

High

967940

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

14

Small-scale

0.501

High

567964

PRG2
Bone marrow proteoglycan

1

4

High-throughput

0.489

High

829512

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.489

High

1339926

OR2M7
Olfactory receptor 2M7

1

2

High-throughput

0.489

High

1339934

OR1M1
Olfactory receptor 1M1

1

3

High-throughput

0.489

High

1339978

OR6T1
Olfactory receptor 6T1

1

3

High-throughput

0.489

High

1406183

KLK15
Kallikrein-15

1

5

High-throughput

0.489

High

1406187

TMM9B
Transmembrane protein 9B

1

2

High-throughput

0.489

High

1406197

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

2

High-throughput

0.489

High

1406198

NHSL3
NHS-like protein 3

1

4

High-throughput

0.489

High

125584

LEG9
Galectin-9

1

2

High-throughput

0.479

High

174063

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

6

High-throughput

0.479

High

229562

NRDC
Nardilysin

1

2

High-throughput

0.479

High

386144

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

18

High-throughput

0.479

High

417704

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.479

High

611311

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

6

High-throughput

0.479

High

634596

LMNB1
Lamin-B1

1

18

High-throughput

0.479

High

837808

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

6

High-throughput

0.479

High

847661

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

895000

EMD
Emerin

1

2

High-throughput

0.479

High

1005015

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1027152

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

1058615

CKAP4
Cytoskeleton-associated protein 4

1

20

High-throughput

0.479

High

1087257

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1333969

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1334523

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

1341005

THOC2
THO complex subunit 2

1

13

High-throughput

0.479

High

1352353

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.479

High

1368361

REQU
Zinc finger protein ubi-d4

1

6

High-throughput

0.479

High

1406182

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.479

High

1406190

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.479

High

1406194

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

291511

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

418384

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

904088

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1111675

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1401211

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1401680

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

0

High-throughput

0.458

High

1404171

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1406177

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1406179

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1406186

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1406189

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1406192

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1406193

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

1406196

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1406199

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1337278

GMCL2
Germ cell-less protein-like 2

1

12

High-throughput

0.445

High

189795

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

1322963

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

1312585

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.426

High

628453

KLK2
Kallikrein-2

1

5

High-throughput

0.407

High

1134154

NTCP
Hepatic sodium/bile acid cotransporter

2

0

High-throughput

0.316

High

1406184

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

1335176

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.279

Low

1361352

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1382045

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025