HitPredict

Interactor 1: FRS2 (Q8WU20)
Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1)
Gene: FRS2

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 214
+	Hs
		894251 FRS2_HUMAN (1-508): 0: 590: 100.00		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		925468 FRS2_HUMAN (1-508): 0: 590: 100.00		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		900731 FRS2_HUMAN (1-508): 0: 590: 100.00		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		436429 FRS2_HUMAN (1-508): 0: 590: 100.00		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		545522 FRS2_HUMAN (1-508): 0: 590: 100.00		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		951184 FRS2_HUMAN (1-508): 0: 590: 100.00		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		564628 FRS2_HUMAN (1-508): 0: 590: 100.00		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		892505 FRS2_HUMAN (1-508): 0: 590: 100.00		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		915865 FRS2_HUMAN (1-508): 0: 590: 100.00		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Hs
		297840 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RHOJ_HUMAN (1-214): 2.19e-84: 250: 100.00
+	Hs
		297823 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		297820 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		297809 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		297812 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		297827 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		297819 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		297822 K0754_HUMAN (89-473): 1.17e-17: 89: 12.29		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44