Interactor 1: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Interactor 2: Q9W414 (Q9W414)
Regulatory particle triple-A ATPase 4 (EC 5.6.1.5)
Gene: Rpt4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 22036573, 19079254, 38944040
Identification Methods affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, AAA~PRS7_OB, PRS7_OB~Prot_ATP_ID_OB_C
Common GO terms GO:0005524 - ATP binding
GO:0005838 - proteasome regulatory particle
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
GO:0036402 - proteasome-activating activity
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 433
Dm

1 397
+ Ce
+ Hs
+ Dm
+ Hs
+ Sp
+ Dm
+ Dm
+ Hs
+ Hs
+ Rn
+ Sp
+ Dm
+ Hs
+ Sp
+ Sc
+ Dm
+ Dm
+ Sc
+ Sc

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Last updated: 11Aug2025