HitPredict

Interactor 1: FLNB (Q80X90)
Filamin-B (FLN-B) (ABP-280-like protein) (Actin-binding-like protein) (Beta-filamin)
Gene: FLNB

Interactor 2: MICA1 (Q8VDP3)
[F-actin]-monooxygenase MICAL1 (EC 1.14.13.225) (EC 1.6.3.1) (Molecule interacting with CasL protein 1) (MICAL-1) (mMical1) (NEDD9-interacting protein with calponin homology and LIM domains)
Gene: Mical1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	21730291
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CH~bMERB_dom, CH~CH, CH~Filamin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2602 Mm			1 1048
+	Hs
		278176 FLNB_HUMAN (1-2602): 0: 2413: 95.85		LIMA1_HUMAN (557-1046): 1.34e-60: 223: 15.63
+	Hs
		224619 FLNA_HUMAN (1-2602): 0: 2235: 68.91		ACTN4_HUMAN (429-1036): 8.34e-100: 337: 13.69
+	Hs
		174704 FLNA_HUMAN (1-2602): 0: 2235: 68.91		SPTN2_HUMAN (457-1038): 8.97e-79: 285: 14.06
+	Hs
		637525 FLNA_HUMAN (1-2602): 0: 2235: 68.91		PLEC_HUMAN (486-1020): 3.24e-74: 272: 14.39
+	Hs
		637778 FLNA_HUMAN (1-2602): 0: 2235: 68.91		LIMA1_HUMAN (557-1046): 1.34e-60: 223: 15.63
+	Dm
		612402 FLNA_DROME (5-2185): 0: 1196: 35.25		ACTN_DROME (467-1043): 9.51e-85: 296: 11.72
+	Dm
		1472954 FLNA_DROME (5-2185): 0: 1196: 35.25		Q9VU34_DROME (547-1045): 7.11e-36: 149: 15.43
+	Hs
		773732 ACTN3_HUMAN (5-413): 3.21e-124: 418: 24.17		ACTN2_HUMAN (458-1043): 7.56e-105: 351: 14.06
+	Hs
		73647 B2R8Y4_HUMAN (5-413): 9.63e-124: 417: 24.17		B2R8Y4_HUMAN (458-1027): 7.55e-102: 343: 14.50
+	Hs
		1061508 ACTN3_HUMAN (5-413): 3.21e-124: 418: 24.17		ACTN3_HUMAN (458-1027): 2.91e-101: 341: 14.33
+	Hs
		555670 ACTN3_HUMAN (5-413): 3.21e-124: 418: 24.17		ACTN1_HUMAN (431-1043): 2.53e-100: 338: 13.71
+	Hs
		224699 ACTN3_HUMAN (5-413): 3.21e-124: 418: 24.17		ACTN4_HUMAN (429-1036): 8.34e-100: 337: 13.69
+	Hs
		73651 B2R8Y4_HUMAN (5-413): 9.63e-124: 417: 24.17		ACTN1_HUMAN (431-1043): 2.53e-100: 338: 13.71
+	Hs
		73649 B2R8Y4_HUMAN (5-413): 9.63e-124: 417: 24.17		ACTN4_HUMAN (429-1036): 8.34e-100: 337: 13.69
+	Rn
		1251028 Q6XD99_RAT (6-370): 7.44e-104: 376: 27.85		ACTN1_RAT (431-1043): 2.56e-100: 338: 13.71
+	Hs
		174744 SPTB2_HUMAN (6-370): 7.5e-104: 376: 27.85		SPTN2_HUMAN (457-1038): 8.97e-79: 285: 14.06
+	Hs
		1061536 ACTN3_HUMAN (5-413): 3.21e-124: 418: 24.17		MILK2_HUMAN (734-1045): 1.2e-36: 151: 20.32
+	Hs
		1061537 ACTN3_HUMAN (5-413): 3.21e-124: 418: 24.17		MILK1_HUMAN (719-1038): 1.85e-29: 128: 17.13
+	Hs
		1028804 SPTB2_HUMAN (6-370): 7.5e-104: 376: 27.85		MICA3_HUMAN (581-1040): 1.2e-31: 136: 19.44
+	Hs
		1028869 SPTB2_HUMAN (6-370): 7.5e-104: 376: 27.85		SPTN4_HUMAN (494-610): 1.81e-11: 70.9: 36.44