Interactor 1: KBTB6 (Q86V97)
Kelch repeat and BTB domain-containing protein 6
Gene: KBTBD6

Interactor 2: KBTB7 (Q8WVZ9)
Kelch repeat and BTB domain-containing protein 7
Gene: KBTBD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 25684205, 26496610, 28514442, 33961781, 33990333, 20562859, unassigned3799
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, comigration in non denaturing gel electrophoresis, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BACK~Kelch_1, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009968 - negative regulation of signal transduction
GO:0031463 - Cul3-RING ubiquitin ligase complex
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 674
Hs

1 684
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025