HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29298432, 40437099
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 953 Hs			1 1593
+	Hs
		773222 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		MYH10_HUMAN (1057-1592): 1.01e-50: 200: 10.75
+	Hs
		772889 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		MYH9_HUMAN (1060-1592): 1.43e-48: 193: 10.09
+	Hs
		1279858 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		RBBP6_HUMAN (1091-1592): 7.8e-28: 125: 13.16
+	Hs
		1290668 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		MINT_HUMAN (1072-1592): 3.44e-26: 120: 12.04
+	Hs
		1121815 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		EIF3A_HUMAN (1162-1555): 7.15e-21: 102: 9.07
+	Hs
		1104966 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		PPIG_HUMAN (1164-1590): 7.87e-21: 101: 14.72
+	Hs
		1212001 ZCH18_HUMAN (1-953): 4.05e-83: 290: 100.00		ZC3HD_HUMAN (1142-1593): 1.43e-12: 75.3: 13.79
+	Hs
		551605 NFH_HUMAN (4-533): 1.97e-38: 157: 11.49		MYH9_HUMAN (1060-1592): 1.43e-48: 193: 10.09
+	Hs
		773158 ANK2_HUMAN (498-952): 3.05e-11: 70.1: 14.63		MYH10_HUMAN (1057-1592): 1.01e-50: 200: 10.75
+	Hs
		772931 TITIN_HUMAN (122-950): 3.41e-13: 76.7: 8.40		MYH9_HUMAN (1060-1592): 1.43e-48: 193: 10.09
+	Hs
		772749 ANK2_HUMAN (498-952): 3.05e-11: 70.1: 14.63		MYH9_HUMAN (1060-1592): 1.43e-48: 193: 10.09
+	Hs
		1129640 MDC1_HUMAN (9-950): 7.49e-10: 65.5: 9.51		MYH14_HUMAN (1057-1589): 4.71e-42: 171: 11.17
+	Dm
		1490102 FUTSC_DROME (3-953): 5.92e-26: 118: 12.14		FUTSC_DROME (1099-1591): 2.14e-15: 84.5: 11.95
+	Hs
		1235637 NIPBL_HUMAN (485-927): 6.33e-11: 68.9: 15.90		NIPBL_HUMAN (1121-1576): 2.51e-21: 104: 13.09
+	Hs
		855429 ANK2_HUMAN (498-952): 3.05e-11: 70.1: 14.63		ATRX_HUMAN (1195-1593): 2.17e-20: 101: 13.22
+	Hs
		1338692 THOC2_HUMAN (248-635): 5.96e-20: 98.2: 14.15		BD1L1_HUMAN (1140-1593): 4.27e-11: 70.7: 15.84
+	Dm
		119668 M9PB30_DROME (298-946): 1.52e-19: 97.5: 8.46		Q9VC60_DROME (1150-1548): 2.42e-09: 64.1: 12.96
+	Hs
		1226570 MAP1S_HUMAN (406-876): 1.7e-13: 77: 16.80		ANR11_HUMAN (1245-1593): 4.75e-09: 63.7: 15.71
+	Hs
		161492 KMT2D_HUMAN (11-944): 4.14e-11: 69.8: 10.97		BD1L1_HUMAN (1140-1593): 4.27e-11: 70.7: 15.84
+	Hs
		1129658 MDC1_HUMAN (9-950): 7.49e-10: 65.5: 9.51		BD1L1_HUMAN (1140-1593): 4.27e-11: 70.7: 15.84