HitPredict

Interactor 1: CYFP2 (Q96F07)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: CYFIP2

Interactor 2: NCKP1 (Q9Y2A7)
Nck-associated protein 1 (NAP 1) (Membrane-associated protein HEM-2) (p125Nap1)
Gene: NCKAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	33961781, 35271311, 37071682, 15048123
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, imaging technique
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FragX_IP~Nckap1
Common GO terms	GO:0000902 - cell morphogenesis GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0030031 - cell projection assembly GO:0031209 - SCAR complex and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 1128
+	Mm
		659515 CYFP2_MOUSE (1-1278): 0: 2126: 97.97		NCKP1_MOUSE (1-1128): 0: 1691: 99.38
+	Hs
		1184675 CYFP1_HUMAN (1-1277): 0: 2040: 85.92		NCKP1_HUMAN (1-1128): 0: 1697: 100.00
+	Mm
		659523 CYFP1_MOUSE (1-1277): 0: 2032: 85.68		NCKP1_MOUSE (1-1128): 0: 1691: 99.38
+	Dm
		876312 CYFIP_DROME (1-1277): 0: 1898: 64.75		HEM_DROME (1-1122): 0: 1545: 59.57
+	Ce
		219536 CYFIP_CAEEL (1-1276): 0: 1747: 50.50		GEX3_CAEEL (8-1121): 0: 1355: 40.52
+	At
		1130829 PIR_ARATH (5-1264): 0: 1510: 28.95		NCKP1_ARATH (70-1126): 0: 1083: 21.54