HitPredict

Interactor 1: SPAST (Q8I0P1)
Spastin (EC 5.6.1.1) (D-Spastin) (Dm-Spastin) (Dspastin)
Gene: spas

Interactor 2: Q95SH2 (Q95SH2)
Charged multivesicular body protein 1, isoform A (Charged multivesicular body protein 1, isoform B) (GH26351p)
Gene: Chmp1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Dm			1 203
+	Hs
		935127 TERA_HUMAN (151-751): 2.34e-152: 465: 21.69		CHM4B_HUMAN (7-198): 1.59e-31: 115: 17.50
+	Hs
		934978 TERA_HUMAN (151-751): 2.34e-152: 465: 21.69		CHM4C_HUMAN (7-186): 2.81e-28: 107: 16.48
+	Hs
		935093 TERA_HUMAN (151-751): 2.34e-152: 465: 21.69		CHM4A_HUMAN (7-198): 1.03e-25: 100: 18.23
+	Sc
		679573 CDC48_YEAST (150-752): 2.95e-145: 448: 21.37		VPS24_YEAST (4-199): 1.69e-28: 107: 12.69
+	Sc
		679960 CDC48_YEAST (150-752): 2.95e-145: 448: 21.37		DID2_YEAST (2-200): 4.83e-26: 100: 42.50
+	Dm
		1377984 Q9Y162_DROME (460-755): 3.39e-119: 367: 39.52		Q95SH2_DROME (1-203): 5.12e-38: 132: 100.00
+	Hs
		221889 SPAST_HUMAN (111-758): 3.65e-120: 375: 43.94		CHM2A_HUMAN (4-182): 6.85e-35: 124: 27.93
+	Hs
		1462137 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHMP3_HUMAN (4-201): 2.42e-36: 128: 16.27
+	Hs
		1462136 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM2B_HUMAN (4-199): 6.86e-35: 124: 18.59
+	Hs
		221893 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM2A_HUMAN (4-182): 6.85e-35: 124: 27.93
+	Hs
		1433102 SPAST_HUMAN (111-758): 3.65e-120: 375: 43.94		CHM4B_HUMAN (7-198): 1.59e-31: 115: 17.50
+	Hs
		1273185 SPAST_HUMAN (111-758): 3.65e-120: 375: 43.94		CHM1B_HUMAN (4-200): 3.17e-31: 114: 72.59
+	Hs
		1439649 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM1A_HUMAN (6-200): 7.48e-34: 121: 49.23
+	Dm
		1482284 Q9Y162_DROME (460-755): 3.39e-119: 367: 39.52		Q9VN02_DROME (4-201): 8.81e-33: 119: 15.71
+	Dm
		1469214 Q9Y162_DROME (460-755): 3.39e-119: 367: 39.52		Q9VBI3_DROME (4-181): 9.99e-32: 117: 26.97
+	Hs
		1433123 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM4B_HUMAN (7-198): 1.59e-31: 115: 17.50
+	Hs
		1273186 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM1B_HUMAN (4-200): 3.17e-31: 114: 72.59
+	Hs
		1385915 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM4C_HUMAN (7-186): 2.81e-28: 107: 16.48
+	Hs
		1417749 VPS4A_HUMAN (424-757): 8.25e-120: 368: 34.41		CHM4A_HUMAN (7-198): 1.03e-25: 100: 18.23
+	Dm
		1345412 Q9Y162_DROME (460-755): 3.39e-119: 367: 39.52		CHM4_DROME (8-182): 6.26e-25: 98.7: 16.20