HitPredict

Interactor 1: Q95SH2 (Q95SH2)
Charged multivesicular body protein 1, isoform A (Charged multivesicular body protein 1, isoform B) (GH26351p)
Gene: Chmp1

Interactor 2: Q9Y162 (Q9Y162)
vesicle-fusing ATPase (EC 3.6.4.6)
Gene: Vps4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 203 Dm			1 442
+	Dm
		1484932 Q9VRJ5_DROME (4-202): 2.12e-39: 136: 19.10		Q9Y162_DROME (1-442): 9.23e-128: 378: 100.00
+	Hs
		1462137 CHMP3_HUMAN (4-201): 2.42e-36: 128: 16.27		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Hs
		1462136 CHM2B_HUMAN (4-199): 6.86e-35: 124: 18.59		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Hs
		221893 CHM2A_HUMAN (4-182): 6.85e-35: 124: 27.93		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Dm
		1482284 Q9VN02_DROME (4-201): 8.81e-33: 119: 15.71		Q9Y162_DROME (1-442): 9.23e-128: 378: 100.00
+	Hs
		221821 CHM2A_HUMAN (4-182): 6.85e-35: 124: 27.93		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	Hs
		276933 CHM2B_HUMAN (4-199): 6.86e-35: 124: 18.59		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	Hs
		1439649 CHM1A_HUMAN (6-200): 7.48e-34: 121: 49.23		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Dm
		1469214 Q9VBI3_DROME (4-181): 9.99e-32: 117: 26.97		Q9Y162_DROME (1-442): 9.23e-128: 378: 100.00
+	Mm
		857265 CHM2A_MOUSE (4-190): 7e-35: 124: 27.27		VPS4B_MOUSE (2-442): 7.58e-125: 371: 75.34
+	Hs
		276925 CHM1A_HUMAN (6-200): 7.48e-34: 121: 49.23		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	Hs
		1433123 CHM4B_HUMAN (7-198): 1.59e-31: 115: 17.50		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Hs
		221889 CHM2A_HUMAN (4-182): 6.85e-35: 124: 27.93		SPAST_HUMAN (62-440): 3.55e-114: 349: 36.84
+	Hs
		1433102 CHM4B_HUMAN (7-198): 1.59e-31: 115: 17.50		SPAST_HUMAN (62-440): 3.55e-114: 349: 36.84
+	Sc
		781329 DID4_YEAST (4-201): 3.93e-36: 127: 22.33		VPS4_YEAST (1-442): 1.17e-110: 334: 57.21
+	At
		1456765 VPS2A_ARATH (3-201): 7.18e-40: 137: 23.59		VPS4_ARATH (4-442): 3.62e-106: 323: 52.24
+	At
		1457066 CHM1B_ARATH (2-200): 3.1e-37: 129: 43.72		VPS4_ARATH (4-442): 3.62e-106: 323: 52.24
+	At
		1082322 VPS2B_ARATH (4-201): 2.03e-35: 126: 24.76		VPS4_ARATH (4-442): 3.62e-106: 323: 52.24
+	Hs
		935127 CHM4B_HUMAN (7-198): 1.59e-31: 115: 17.50		TERA_HUMAN (113-437): 4.95e-71: 241: 28.05
+	Dm
		1301207 Q95SH2_DROME (1-203): 5.12e-38: 132: 100.00		SPAST_DROME (111-354): 2.57e-62: 216: 49.19