HitPredict

Interactor 1: Q9VN02 (Q9VN02)
GH14561p (Vacuolar protein sorting 24, isoform A) (Vacuolar protein sorting 24, isoform B)
Gene: Vps24

Interactor 2: Q9Y162 (Q9Y162)
vesicle-fusing ATPase (EC 3.6.4.6)
Gene: Vps4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 223 Dm			1 442
+	Hs
		1462137 CHMP3_HUMAN (1-223): 9.55e-53: 171: 58.74		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Dm
		1484932 Q9VRJ5_DROME (2-209): 5.43e-45: 151: 27.40		Q9Y162_DROME (1-442): 9.23e-128: 378: 100.00
+	Hs
		221893 CHM2A_HUMAN (3-222): 1.37e-45: 152: 22.73		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Mm
		857265 CHM2A_MOUSE (3-222): 1.31e-46: 155: 22.73		VPS4B_MOUSE (2-442): 7.58e-125: 371: 75.34
+	Dm
		1469214 Q9VBI3_DROME (3-202): 2.95e-43: 147: 23.50		Q9Y162_DROME (1-442): 9.23e-128: 378: 100.00
+	Hs
		1462136 CHM2B_HUMAN (9-204): 7.49e-45: 150: 22.45		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Hs
		221821 CHM2A_HUMAN (3-222): 1.37e-45: 152: 22.73		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	Hs
		276933 CHM2B_HUMAN (9-204): 7.49e-45: 150: 22.45		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	Dm
		1377984 Q95SH2_DROME (23-222): 3.93e-38: 132: 16.50		Q9Y162_DROME (1-442): 9.23e-128: 378: 100.00
+	Hs
		1439649 CHM1A_HUMAN (22-223): 2.67e-37: 130: 11.39		VPS4A_HUMAN (6-441): 4.97e-126: 374: 73.85
+	Hs
		276925 CHM1A_HUMAN (22-223): 2.67e-37: 130: 11.39		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	Hs
		221889 CHM2A_HUMAN (3-222): 1.37e-45: 152: 22.73		SPAST_HUMAN (62-440): 3.55e-114: 349: 36.84
+	At
		1456765 VPS2A_ARATH (2-222): 2.79e-55: 177: 23.87		VPS4_ARATH (4-442): 3.62e-106: 323: 52.24
+	Sc
		781329 DID4_YEAST (3-222): 1.3e-50: 166: 21.78		VPS4_YEAST (1-442): 1.17e-110: 334: 57.21
+	Hs
		276910 CHM1B_HUMAN (23-223): 2.59e-35: 125: 13.93		VPS4B_HUMAN (2-442): 1.93e-125: 372: 74.21
+	At
		1082322 VPS2B_ARATH (1-222): 4.52e-50: 164: 24.32		VPS4_ARATH (4-442): 3.62e-106: 323: 52.24
+	Sc
		781012 VPS24_YEAST (10-223): 4.85e-43: 146: 30.23		VPS4_YEAST (1-442): 1.17e-110: 334: 57.21
+	At
		1457066 CHM1B_ARATH (22-217): 6.17e-40: 137: 16.84		VPS4_ARATH (4-442): 3.62e-106: 323: 52.24
+	Sc
		679573 VPS24_YEAST (10-223): 4.85e-43: 146: 30.23		CDC48_YEAST (128-437): 4.54e-71: 241: 30.35
+	Dm
		1301207 Q95SH2_DROME (23-222): 3.93e-38: 132: 16.50		SPAST_DROME (111-354): 2.57e-62: 216: 49.19