Interactor 1: Q29QQ9 (Q29QQ9)
Ribosomal RNA-processing protein 42
Gene: Rrp42

Interactor 2: EXOS3 (Q8IPX7)
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)
Gene: Rrp40

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~Rrp40_N, RNase_PH~RRP40_S1
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
and 4 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 296
Dm

1 232
+ Hs
+ Hs
+ Dm
+ Hs
+ Sp
+ Dm
+ At
+ Hs
+ At
+ Sc
+ Sc
+ Sc

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Last updated: 11Aug2025