Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 32157086, 32631902, 33961781, 35271311, 26496610, 27428775, 28821611, 28292943, 30745168, 35530310, 37071682, 17323924
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0022624 - proteasome accessory complex
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 310
Hs

1 418
+ At
+ Dm
+ Dm
+ Dm
+ Sp
+ Hs
+ Dm
+ Hs
+ Hs
+ Sp
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ At
+ At
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024