Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.724

The method score is based on:

Property Details
Experiments 30425250, 31740976, 19615732, 27428775, 30745168, 35530310
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005829 - cytosol
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061136 - regulation of proteasomal protein catabolic process
GO:0061578 - K63-linked deubiquitinase activity
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 310
Hs

1 494
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024